Bariatric surgery and liver transplantation, here we are now: A French nationwide retrospective study - 11/08/23
for the
Groupe de recherche français en Greffe de Foie (GReF2)b
Abstract |
At the time of the growing obesity epidemic worldwide, liver transplantation (LT) and metabolic syndrome are closely linked: non-alcohol-related fatty liver disease (NAFLD) is one of the leading indications for liver transplantation, and metabolic syndrome can also appear after liver transplantation, in relation to immunosuppressive medications and weight gain, whatever was the initial liver disease leading to the indication of LT. Therefore, the role of bariatric surgery (BS) is important due to its longer-lasting effect and efficacy. We performed a retrospective review of all 50 adult French liver transplant recipients who had a history of bariatric surgery, including 37 procedures before transplantation, and 14 after. There were three significantly different characteristics when comparing pre-and post-LT BS: patients were older (at the time of BS), presented more frequently arterial hypertension (at the time of LT), and the proportion of NAFLD as initial liver disease leading to LT was lower, in the post-LT group. Regarding pre-LT BS, in one case BS was complicated by liver failure leading to the rapid indication of LT; it was the single patient for whom the delay between BS and LT was less than 1 year; there was no patient who specifically underwent BS for the purpose of LT listing.
Le texte complet de cet article est disponible en PDF.Keywords : Liver transplantation, Metabolic syndrome, Nafld, Obesity, Bariatric surgery
Abbreviations : BS, HCC, LT, MS, NAFLD
Plan
Vol 47 - N° 7
Article 102164- août 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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