Prospective cohort of COVID-19 patients requiring hospital admission in Douala, Cameroon - 27/07/23
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Highlights |
• | Data on COVID-19 patients hospitalized in low-income countries are scarce. |
• | In clinics with no access to mechanical ventilation, the 28-day mortality was 24%. |
• | Most patients (>95%) received oxygen support, steroids, and anticoagulants. |
Abstract |
Objectives |
To report characteristics and outcome of COVID-19 patients who required hospital admission in sub-Saharan Africa clinics with no access to invasive mechanical ventilation.
Methods |
Between April and June 2021, documented COVID-19 patients with SaO2 < 95% who were admitted in two clinics in Douala (Cameroon) were invited to participate. Data were prospectively collected using a standardized questionnaire.
Results |
We included 67 patients: 39 males (58%), median age 62 years [50–70]. Comorbidities included hypertension (n = 38, 57%), obesity (n = 26, 38%), and diabetes (n = 16, 24%). No patient reported COVID-19 vaccination. On admission, 35 patients (52%) required O2 > 6 L/min. CT scan demonstrated extended lesions (>50%) in 50/61 cases (82%). Most patients received dexamethasone (n = 64, 96%), heparin (n = 64, 96%), chloroquine/azithromycin (n = 59, 88%), and broad-spectrum antibiotics (n = 59, 88%). Sixteen patients died (24%), after a median of 11.5 days [7.5–15.5] post-admission.
Conclusions |
Despite the lack of invasive mechanical ventilation, 76% of COVID-19 patients survived.
Le texte complet de cet article est disponible en PDF.Keywords : COVID-19, Intensive care unit, Cameroon, Mechanical ventilation, Prognosis
Plan
Vol 53 - N° 5
Article 104713- août 2023 Retour au numéro
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