Considerations in Children and Adolescents Related to Coronavirus Disease 2019 (COVID-19) - 06/07/23

Doi : 10.1016/j.pmr.2023.03.004

Erin Y. Chen, BS ^a, Justin M. Burton, MD ^b, Alicia Johnston, MD ^c, Amanda K. Morrow, MD ^d,^e, Alexandra B. Yonts, MD ^f, Laura A. Malone, MD, PhD ^d,^e,^g,^⁎
^a Johns Hopkins School Medicine, 733 North Broadway, Baltimore, MD 21205, USA
^b Division of Pediatric Rehabilitation Medicine, Children’s National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA
^c Division of Infectious Disease, Boston Children’s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
^d Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
^e Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
^f Division of Infectious Diseases, Children’s National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA
^g Department of Neurology, Johns Hopkins School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA

^∗Corresponding author. 707 North Broadway, Baltimore, MD 21205.707 North BroadwayBaltimoreMD21205

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Résumé

Pediatric post-acute sequelae of SARS-CoV-2 (PASC) or “long COVID” are a complex multisystemic disease that affects children’s physical, social, and mental health. PASC has a variable presentation, time course, and severity and can affect children even with mild or asymptomatic acute COVID-19 symptoms. Screening for PASC in children with a history of SARS-CoV-2 infection is important for early detection and intervention. A multifaceted treatment approach and utilization of multidisciplinary care, if available, are beneficial in managing the complexities of PASC. Lifestyle interventions, physical rehabilitation, and mental health management are important treatment approaches to improve pediatric PASC patients’ quality of life.

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Keywords : Post-acute sequelae of SARS-CoV-2, Long COVID, Multidisciplinary care, SARS-CoV-2, Pediatrics, Rehabilitation, Fatigue, Quality of life

Plan

Key points

Introduction

Symptoms and presentation of pediatric post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Multisystem inflammatory syndrome in children

Potential mechanisms of post-acute sequelae of SARS-CoV-2

Treatment of pediatric post-acute sequelae of SARS-CoV-2

Current Treatment Approaches for Overall Systems

Multidisciplinary Care Approach

Discussion and limitations

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Vol 34 - N° 3

P. 643-655 - août 2023 Retour au numéro

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Considerations in Children and Adolescents Related to Coronavirus Disease 2019 (COVID-19) - 06/07/23

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