Duration of Fecal Excretion of Clostridium Botulinum and Botulinum Neurotoxin in Patients Recovering from Infant Botulism - 05/07/23
Doi : 10.1016/j.jpeds.2023.113396
Haydee A. Dabritz, PhD, Jessica R. Payne, MPH ∗, Jessica M. Khouri, MD ⁎ 
Infant Botulism Treatment and Prevention Program, Infectious Diseases Laboratories Division, Center for Laboratory Sciences, California Department of Public Health, Richmond, CA
∗Reprint requests: Dr Jessica M. Khouri, MD, Infant Botulism Treatment and Prevention Program, California Department of Public Health, 850 Marina Bay Pkwy, Room E-361, Richmond, CA 94804Infant Botulism Treatment and Prevention ProgramCalifornia Department of Public Health850 Marina Bay PkwyRoom E-361RichmondCA94804
Abstract |
This study sought to determine duration of fecal excretion of Clostridium botulinum organisms and neurotoxin after onset of infant botulism in 66 affected infants. Median excretion was longer for type A than type B patients (organisms: 5.9 vs 3.5 weeks, toxin: 4.8 vs 1.6 weeks, respectively). Toxin excretion always ceased before organism excretion. Antibiotic therapy did not affect duration of excretion.
Le texte complet de cet article est disponible en PDF.Keywords : infant botulism, fecal excretion, Clostridium botulinum, detection, botulinum toxin
Abbreviations : BIG-IV, BoNT, IB
Plan
| This work was supported by the Infant Botulism Treatment and Prevention Fund of the California Department of Public Health. The authors have no conflicts of interest to disclose. |
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| The findings and conclusions in this article are those of the authors and do not necessarily represent the views or opinions of the California Department of Public Health or the California Health and Human Services Agency. |
© 2023
Elsevier Inc. Tous droits réservés.
Vol 258
Article 113396- juillet 2023 Retour au numéro
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