Delayed-Onset Transient Hyperinsulinism in Infants with Very Low and Extremely Low Birth Weights: A Cohort Study - 05/07/23
Doi : 10.1016/j.jpeds.2023.113399
Henrike Hoermann, MD ⁎ 
, Marcia Roeper, MD, Alena Welters, MD, Fabian Baertling, MD, Ertan Mayatepek, MD, Thomas Meissner, MD, Sebastian Kummer, MD
, Marcia Roeper, MD, Alena Welters, MD, Fabian Baertling, MD, Ertan Mayatepek, MD, Thomas Meissner, MD, Sebastian Kummer, MD Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany
∗Reprint requests: Dr Henrike Hoermann, MD, Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children’s Hospital, Heinrich-Heine-University, Moorenstraße 5, Düsseldorf 40225, Germany.Department of General PediatricsNeonatology and Pediatric CardiologyUniversity Children’s HospitalHeinrich-Heine-UniversityMoorenstraße 5Düsseldorf40225Germany
Abstract |
We describe 16 infants born preterm with birth weights <1500 g and transient hyperinsulinism. The onset of hyperinsulinism was delayed and often coincident with clinical stabilization. We hypothesize that postnatal stress caused by prematurity and associated problems may contribute to development of delayed-onset transient hyperinsulinism.
Le texte complet de cet article est disponible en PDF.Keywords : hypoglycemia, blood glucose, neonatal glycemia, prematurity
Abbreviation : ELBW, VLBW
Plan
| This investigator-initiated research study was funded by a research grant from Zealand Pharma A/S (Søborg, Denmark). The funder had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript and in the decision to submit the manuscript for publication. S.K. and T.M. have been involved in contract research for Zealand Pharma. The other authors have no conflicts of interest to disclose. |
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| Data were presented as a poster at the European Society for Paediatric Endocrinology annual meeting, September 15-17, 2022, Rome, Italy. |
© 2023
Elsevier Inc. Tous droits réservés.
Vol 258
Article 113399- juillet 2023 Retour au numéro
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