Severe atypical Lemierre syndrome caused by methicillin-sensitive Staphylococcus aureus: Two pediatric case reports - 22/06/23

Doi : 10.1016/j.arcped.2023.02.007

R. El Hajj ^a, A. Stanzelova ^b,^c, C. de Marcellus ^d, M. Kossorotoff ^e, F. Remangeon ^c,^f, C.-J. Roux ^g, R. Touzé ^h,^c, J. Toubiana ^b,^c, S. Benaboud ⁱ, M. Oualha ^c,^d, F. Moulin ^d, C. Collignon ^d,^⁎
^a Pediatrics, André Mignot Hospital, Versailles, France
^b Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants Malades University Hospital, Paris, France
^c Université de Paris Cité, Paris, France
^d Pediatric Intensive Care Unit, APHP University Hospital Necker-Enfants Malades, Paris, France
^e Pediatric Neurology, APHP University Hospital Necker-Enfants Malades, Paris, France
^f Pediatric Otorhinolaryngology Department, APHP, Hôpital Universitaire Necker-Enfants Malades, Paris, France
^g Pediatric Radiology, APHP University Hospital Necker-Enfants Malades, Paris, France
^h Ophthalmology Department and Reference Center for Rare Ophthalmological Diseases (OPHTARA), AP-HP, University Hospital Necker-Enfants Malades, Paris, France
ⁱ Pharmacology Department, Cochin Hospital, AP-HP Centre-Université de Paris, Paris, France

^⁎Corresponding author at: Pediatric Intensive Care Unit, Necker-Enfants Malades University Hospital, 149 rue de Sèvres, 75015 Paris, France.Pediatric Intensive Care UnitNecker-Enfants Malades University Hospital149 rue de SèvresParis75015France

Abstract

Background

Lemierre syndrome is typically associated with ear, nose, and throat (ENT) infections caused by Fusobacterium necrophorum. Since 2002, cases of atypical Lemierre-like syndrome secondary to Staphylococcus aureus have been reported.

Cases

We report two pediatric cases of atypical Lemierre syndrome with a similar presentation: exophthalmia, absence of pharyngitis, metastatic lung infection, and intracranial venous sinus thrombosis. Both patients had a favorable outcome following treatment with antibiotics, anticoagulation, and corticosteroids.

Conclusion

Regular therapeutic monitoring of antibiotic levels helped to optimize antimicrobial treatment in both cases.

Le texte complet de cet article est disponible en PDF.

Keywords : Lemierre syndrome, Staphylococcus aureus, Pediatric intensive care, Therapeutic drug monitoring

Plan

Export

Vol 30 - N° 5

P. 343-346 - juillet 2023 Retour au numéro

Article précédent

Temporomandibular disorders in children and adolescents: A review
C. Mélou, J.L. Sixou, C. Sinquin, D. Chauvel-Lebret

| Article suivant

A French nationwide survey of phototherapy in very preterm and moderately preterm infants
C. Szcrupak, P. Tourneux

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

Déjà abonné à cette revue ?

connectez-vous ou créez un compte

Severe atypical Lemierre syndrome caused by methicillin-sensitive Staphylococcus aureus: Two pediatric case reports - 22/06/23

Abstract

Background

Cases

Conclusion

Plan

Export citations

Fichier

Contenu

Accès rapides

Mon compte

Aide & support

Plateformes Elsevier Masson

Déclaration CNIL