Symptoms of Long-COVID 1-Year after a COVID-19 outbreak among sailors on a French aircraft carrier - 16/06/23
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Highlights |
• | Prevalence of Long-COVID symptoms was 53.7%, 55.2% and 54.3% in COVID-positive patients at months 6, 9 and 12. |
• | In COVID-negative patients, prevalence was 31.2%, 23.3% and 40.0% at months 6, 9 and 12. |
• | The main symptoms were concentration difficulties, asthenia and sleep disorders. |
• | Mild COVID-19 patients reported more symptoms than negative patients during the first 9 months. |
• | We should evoke a differential diagnosis in case of symptoms 1 year after mild-COVID. |
Abstract |
Objectives |
While persistent symptoms have been reported after the coronavirus disease-2019 (COVID-19), long-term data on outpatients with mild COVID-19 are lacking. The objective was to describe symptoms persisting for 12 months.
Methods |
This prospective cohort study on 1767 sailors of an aircraft carrier in which a Covid-19 outbreak occurred during a mission in April 2020 described predefined self-reported symptoms of Long-COVID at 6, 9 and 12 months. Logistic-regression analyses were used to identify correlates for Long-COVID at months 6, 9 and 12.
Results |
Among the 641 participants, 619 (35%) completed at least one follow-up questionnaire (413 COVID-positive and 206 COVID-negative). Symptoms of Long-COVID were reported by 53.7%, 55.2% and 54.3% of COVID-positive participants vs 31.2%, 23.3% and 40.0% in COVID-negative patients, at 6 (p <.002), 9 (p <.002) and 12 months (p =.13), respectively. The most frequent symptoms reported were concentration and memory difficulties, asthenia and sleep disorders.
Conclusion |
In this study more than half of COVID-positive outpatients reported persistent symptoms up to 12 months post-quarantine. These findings suggests that all patients, including those with mild disease, can be affected by Long-COVID. A lack of difference at 12 months with COVID-negative patienys prompts caution. The symptoms of Long-COVID are so non-specific that they may be viewed as the consequence of multiple intercurrent factors.
Le texte complet de cet article est disponible en PDF.Keywords : SARS-CoV2, Symptoms of Long-COVID, Aircraft-carrier, Long term symptoms
Plan
Vol 53 - N° 4
Article 104673- juin 2023 Retour au numéro
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