Gastric immune homeostasis imbalance: An important factor in the development of gastric mucosal diseases - 28/03/23


Abstract |
The gastric mucosal immune system is a unique immune organ independent of systemic immunity that not only maintains nutrient absorption but also plays a role in resisting the external environment. Gastric mucosal immune disorder leads to a series of gastric mucosal diseases, including autoimmune gastritis (AIG)-related diseases, Helicobacter pylori (H. pylori)-induced diseases, and various types of gastric cancer (GC). Therefore, understanding the role of gastric mucosal immune homeostasis in gastric mucosal protection and the relationship between mucosal immunity and gastric mucosal diseases is very important. This review focuses on the protective effect of gastric mucosal immune homeostasis on the gastric mucosa, as well as multiple gastric mucosal diseases caused by gastric immune disorders. We hope to offer new prospects for the prevention and treatment of gastric mucosal diseases.
Le texte complet de cet article est disponible en PDF.Graphical Abstract |
Highlights |
• | Different gastric mucosal diseases caused by imbalance of gastric mucosal immune homeostasis. |
• | Explain the composition and function of gastric mucosal immune homeostasis. |
• | There is interaction between gastric epithelial cells (GEC) and immune cells. |
• | Explain the possible molecular mechanism of the occurrence and development of gastric mucosal diseases. |
Keywords : Gastric mucosal immunity, Gastric immune disorder, Multiple gastric mucosa diseases
Plan
Vol 161
Article 114338- mai 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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