Discrepancies in survival after conversion to open in minimally invasive pancreatoduodenectomy - 16/03/23
![](/templates/common/images/mail.png)
![](/templates/common/images/mail.png)
Abstract |
Background |
The extent by which conversion to open (CTO) during minimally invasive procedures for pancreatic cancer impact survival outcomes is not fully understood.
Methods |
The 2010–2017 National Cancer Database identified 12,424 non-metastatic patients who underwent pancreatoduodenectomy for ductal adenocarcinoma. Patients were stratified into three cohorts: open (OPD), completed MIPD (cMIPD), and CTO. Subgroups were dichotomized by hospital MIPD volume.
Results |
Across the study period, 80.6% of patients underwent OPD, 19.4% MIPD, and 24% were CTO. Median overall survival was worse after CTO (21.8 months) than for OPD (23.6 months) or cMIPD (25.2 months) (p < 0.001). Although this effect persisted for <10 MIPD/year, CTO did comparably to OPD at hospitals performing ≥10MIPD/year (CTO = 26.8 months, OPD = 27.9 months; p = 0.128). Ninety-day mortality after CTO was worse at ≤ 10 MIPD/year hospitals (9.3% vs. 2.6%).
Conclusions |
Short and long-term survival is impacted by CTO after MIPD, especially at lower surgical volumes, stressing careful adoption while ascending the learning curve.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | Minimally invasive pancreatoduodenectomy has become increasingly popular with concomitant decreases in conversion to open. |
• | Conversion to open pancreatoduodenectomy is associated with a lower median overall survival than successful open operations. |
• | 90-day mortality after conversion to open from minimally invasive pancreatoduodenectomy is higher at low-volume centers. |
• | These data emphasize the importance of safe adoption strategies when learning minimally invasive pancreatoduodenectomy. |
Keywords : Pancreas, Cancer, Minimally invasive, Conversion, Survival, Outcomes
Plan
Vol 225 - N° 4
P. 728-734 - avril 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?