Varying impact of patient age on the rising rate of pediatric thyroid cancer: Analysis of NCDB database (2004–2017) - 07/03/23
Abstract |
Pediatric thyroid carcinoma is on the rise. We sought to better characterize patient factors associated with this and evaluate for trends based on age groups. Additionally, we examined surgical management over time, and whether it aligns with recommendations made by the American Thyroid Association. Using the National Cancer Database (NCDB), we examined cases of thyroid cancer from 2004 to 2017, ages 1–18 years. We subdivided this cohort by age group: those <10y, 10-15y, and >15y. NCDB query yielded 5,814 cases. The annual proportion of total cases ranged from 3% to 8% for <10y, 31%–40% for 10-15y, and 52%–66% for >15y. 80–90% of cases in all age groups did indeed receive total thyroidectomy which is consistent with ATA guidelines. Our results verify an overall increase in pediatric thyroid cancer cases, occurring mostly in the 10–18 years old age range with the largest year-to-year increases in the >15y group.
Le texte complet de cet article est disponible en PDF.Highlights |
• | We demonstrated that becoming an adolescent is associated with an increased risk to develop thyroid cancer. |
• | There were more pediatric thyroid cancer cases in female (>80%) than male, which is suggestive of a hormonal association. |
• | Most cases (∼90%) underwent total thyroidectomy, aligning with ATArecommendations, both prior to and after their publication. |
• | To better discern the role of puberty on thyroid cancer development, standardized criteria are needed to categorize puberty. |
Keywords : Endocrine surgery, Endocrine, Pediatric thyroid cancer
Plan
Vol 225 - N° 3
P. 532-536 - mars 2023 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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