How respiratory symptoms impact asthma-related quality of life in mild asthmatics - 07/02/23

Doi : 10.1016/j.rmed.2022.107098

Gilles Louis ^a,^⁎ , Florence Schleich ^b, Renaud Louis ^b, Michèle Guillaume ^a, Bernardo Sousa-Pinto ^c, Jean Bousquet ^d,^e,^f, Benoit Pétré ^a
^a Department of Public Health, University of Liège, Belgium
^b Department of Pneumology, GIGAI3, University of Liège, Belgium
^c Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal
^d Institute of Allergology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
^e Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany
^f University Hospital Montpellier, France

^∗Corresponding author.

Abstract

Many studies exploring the factors associated with asthma-specific quality of life (QOL) have shown that asthma control is the main predictor of asthma-related QOL. However, to the best of our knowledge, no study has ever explored the individual impact of the five main symptoms of asthma (wheezing, dyspnea, chest tightness, cough and airway secretion) reported directly by the patient on asthma-related QOL. A cross-sectional study was conducted on untreated adult (≥18 years) asthmatics recruited from the Liege University Hospital Asthma Clinic (Belgium) for asthma diagnosis confirmation between 2018 and 2021 (n = 171). Multiple linear regression analysis demonstrated that dyspnea and chest tightness were the two leading factors associated with asthma-related QOL in a population of mild asthma.

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Highlights

•	Knowing which specific symptoms have the greatest impact on the daily lives of asthmatics is fundamental for improving patient's management.
•	This is the first study to explore the impact of the five main symptoms of asthma reported directly by the patient on asthma-related quality of life.
•	This study shows that each symptom harbors specific value helping to refine the understanding of the disease and its management.

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Keywords : Asthma, Quality of life, Symptoms, PROM

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Vol 207

Article 107098- février 2023 Retour au numéro

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How respiratory symptoms impact asthma-related quality of life in mild asthmatics - 07/02/23

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