Effect of a SARS-CoV-2 booster vaccine dose on the immune response of adults with Down syndrome - 28/01/23
Doi : 10.1016/j.jinf.2022.11.014
Ayla Yarci-Carrión a, Laura Esparcia-Pinedo b, Gloria Mateo-Jiménez c, Arantzazu Alfranca b, d, Diego Real de Asúa d, e, ⁎ 
, Ainhoa Gutiérrez-Cobos a
, Ainhoa Gutiérrez-Cobos a a Microbiology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
b Immunology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
c Fundación de Investigación Biomédica del Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
d Department of Medicine, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain
e Internal Medicine Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Diego de León 62, Madrid 28006, Spain
⁎Corresponding author at: Internal Medicine Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Diego de León 62, Madrid 28006, SpainInternal Medicine Department, Hospital Universitario de La PrincesaInstituto de Investigación Sanitaria PrincesaDiego de León 62Madrid28006Spain
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Highlights |
• | Immune protection granted by COVID-19 vaccines wanes over time. |
• | Individuals with Down syndrome (DS) are considered an at-risk population for COVID-19 hospitalization and death. |
• | Our findings show that a booster COVID-19 vaccine dose promotes a renewed, effective cellular and humoral immune response in adults with DS, akin to the general population. |
Keywords : Down syndrome, COVID-19, SARS-CoV-2, Vaccination, Immune system
Plan
| ☆ | All authors contributed equally to the manuscript and share first authorship. |
© 2022
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 86 - N° 2
P. 154-225 - février 2023 Retour au numéro
Article précédent
- Inactivated COVID-19 vaccination and maternal renal function during early pregnancy: A retrospective cohort study of 6397 Chinese pregnant women
- Yan Zhao, Yongbo Zhao, Yicheng Zhou, Ziyi Zhang, Yijun Zhang, Mengyuan Li, Xin Su, Liping Jin
- Serological response to COVID-19 vaccine and its predictors in patients with solid malignancies: A systematic review and meta-analysis of 16 cohort studies
- Dong Chen, Yuancan Pan, Yue Wang, Xing Chen, Jiahui Zhang, Yutong Zhang, Tongjing Ding, Zhengzheng Yang, Taicheng Lu, Yingying Zheng, Jiangyan Wei, Weijia Kong, Haiming Li, Xiaohui Yin, Guowang Yang, Ganlin Zhang, Xiaomin Wang
Bienvenue sur EM-consulte, la référence des professionnels de santé.