S'abonner

Mechanical Circulatory Support in Patients With COVID-19 Presenting With Myocardial Infarction - 13/12/22

Doi : 10.1016/j.amjcard.2022.09.030 
Raviteja R. Guddeti, MD a, Cristina Sanina, MD b, Rajiv Jauhar, MD c, Timothy D. Henry, MD d, Payam Dehghani, MD e, Ross Garberich, MS, MBA a, Christian W. Schmidt, MS b, Keshav R. Nayak, MD f, Jay S. Shavadia, MD g, Akshay Bagai, MD, MHS h, Chadi Alraies, MD i, Aditya Mehra, MD j, Rodrigo Bagur, MD, PhD k, Cindy Grines, MD l, Avneet Singh, MD c, Rajan A.G. Patel, MD m, Wah Wah Htun, MD n, Nima Ghasemzadeh, MD o, Laura Davidson, MD p, Deepak Acharya, MD q, Ameer Kabour, MD r, Abdul Moiz Hafiz, MD s, Shy Amlani, MD t, Hal S. Wasserman, MD u, Timothy Smith, MD d, Navin K. Kapur, MD v, Santiago Garcia, MD d,
a Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, Minnesota 
b Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 
c North Shore University Hospital, Manhasset, New York 
d The Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio 
e Prairie Vascular Research, Regina, Saskatchewan, Canada 
f Department of Cardiology, Scripps Mercy Hospital, San Diego, California 
g Royal University Hospital, University of Saskatchewan Saskatoon, Saskatchewan, Canada 
h St Michael's Hospital, Toronto, Ontario, Canada 
i DMC Harper University Hospital, Detroit, Michigan 
j Jersey Shore University Medical Center, Neptune, New Jersey 
k London Health Sciences Centre, London, Ontario, Canada 
l Northside Hospital Cardiovascular Institute, Atlanta, Georgia 
m Ochsner Health, University of Queensland Ochsner Clinical School, New Orleans, Louisiana 
n Gunderson Health, Onalaska, Wisconsin 
o Georgia Heart Institute, Gainesville, Georgia 
p Northwestern University, Evanston, Illinois 
q University of Arizona Sarver Heart Center, Tuczon, Arizona 
r Mercy St Vincent's Medical Center, Toledo, Ohio 
s Southern Illinois University School of Medicine. Springfiled, Illinois 
t William Osler Health System, Ontario, Canada 
u Nuvance Health, Danbury Hospital. Danbury, Connecticut 
v Tufts Medical Center, Boston, Massachusetts 

Corresponding author: Tel: 513-321-0875; fax: 513-585-1510.

Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.

Connectez-vous pour en bénéficier!

Résumé

ST-segment elevation myocardial infarction (STEMI) complicating COVID-19 is associated with an increased risk of cardiogenic shock and mortality. However, little is known about the frequency of use and clinical impact of mechanical circulatory support (MCS) in these patients. We sought to define patterns of MCS utilization, patient characteristics, and outcomes in patients with COVID-19 with STEMI. The NACMI (North American COVID-19 Myocardial Infarction) is an ongoing prospective, observational registry of patients with COVID-19 positive (COVID-19+) with STEMI with a contemporary control group of persons under investigation who subsequently tested negative for COVID-19 (COVID-19−). We compared the baseline characteristics and in-hospital outcomes of COVID-19+ and patients with COVID-19− according to the use of MCS. The primary outcome was a composite of in-hospital mortality, stroke, recurrent MI, and repeat unplanned revascularization. A total of 1,379 patients (586 COVID-19+ and 793 COVID-19−) enrolled in the NACMI registry between January 2020 and November 2021 were included in this analysis; overall, MCS use was 12.3% (12.1% [n = 71] COVID-19+/MCS positive [MCS+] vs 12.4% [n = 98] COVID-19−/MCS+). Baseline characteristics were similar between the 2 groups. The use of percutaneous coronary intervention was similar between the groups (84% vs 78%; p = 0.404). Intra-aortic balloon pump was the most frequently used MCS device in both groups (53% in COVID-19+/MCS+ and 75% in COVID-19−/MCS+). The primary outcome was significantly higher in COVID-19+/MCS+ patients (60% vs 30%; p = 0.001) because of very high in-hospital mortality (59% vs 28%; p = 0.001). In conclusion, patients with COVID-19+ with STEMI requiring MCS have very high in-hospital mortality, likely related to the significantly higher pulmonary involvement compared with patients with COVID-19− with STEMI requiring MCS.

Le texte complet de cet article est disponible en PDF.

Plan


 This work was supported by the Society for Cardiovascular Angiography and Interventions (Washington, District of Columbia), American College of Cardiology Accreditation Grant (Washington, District of Columbia), Canadian Association of Interventional Cardiology (Ottawa, Ontario, Canada), Medtronic (Dublin, Ireland), and Abbott Vascular (Chicago, Illinois).


© 2022  Elsevier Inc. Tous droits réservés.
Ajouter à ma bibliothèque Retirer de ma bibliothèque Imprimer
Export

    Export citations

  • Fichier

  • Contenu

Vol 187

P. 76-83 - janvier 2023 Retour au numéro
Article précédent Article précédent
  • Meta-Analysis on the Clinical Outcomes of Transcatheter Aortic Valve Implantation in Low-Surgical Risk Patients With Bicuspid Aortic Valves
  • Elham Mahmoudi, Rahul Gupta, Amir Hossein Behnoush, Apurva V. Vyas, Nainesh C. Patel
| Article suivant Article suivant
  • Gender Differences in Age-Stratified Early Outcomes in Patients With Transcatheter Aortic Valve Implantation
  • Chi Zhou, Zongyi Xia, Bing Chen, Yanxu Song, Zhexun Lian

Bienvenue sur EM-consulte, la référence des professionnels de santé.

Mon compte


Plateformes Elsevier Masson

Déclaration CNIL

EM-CONSULTE.COM est déclaré à la CNIL, déclaration n° 1286925.

En application de la loi nº78-17 du 6 janvier 1978 relative à l'informatique, aux fichiers et aux libertés, vous disposez des droits d'opposition (art.26 de la loi), d'accès (art.34 à 38 de la loi), et de rectification (art.36 de la loi) des données vous concernant. Ainsi, vous pouvez exiger que soient rectifiées, complétées, clarifiées, mises à jour ou effacées les informations vous concernant qui sont inexactes, incomplètes, équivoques, périmées ou dont la collecte ou l'utilisation ou la conservation est interdite.
Les informations personnelles concernant les visiteurs de notre site, y compris leur identité, sont confidentielles.
Le responsable du site s'engage sur l'honneur à respecter les conditions légales de confidentialité applicables en France et à ne pas divulguer ces informations à des tiers.


Tout le contenu de ce site: Copyright © 2024 Elsevier, ses concédants de licence et ses contributeurs. Tout les droits sont réservés, y compris ceux relatifs à l'exploration de textes et de données, a la formation en IA et aux technologies similaires. Pour tout contenu en libre accès, les conditions de licence Creative Commons s'appliquent.