Outcomes of surgical bioprosthetic aortic valve replacement for aortic insufficiency - 02/12/22
, Evaldas Girdauskas c, d, Anissa Aissani a, Matthieu Debauchez a, Guillaume Lebreton a, Pascal Leprince a, Hermann Reichenspurner c, Johannes Petersen c, Emmanuel Lansac a
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Highlights |
• | Aortic valve replacement for aortic insufficiency has good short-term results. |
• | However, mortality at 10 years in young patients may be important. |
• | Durability of aortic valve replacement in this indication was good. |
Abstract |
Background |
Results and durability of aortic valve replacement in aortic stenosis are well known, but no study has focused on the results of aortic valve replacement in aortic insufficiency.
Aim |
The aim of this retrospective study was to describe our mid-term outcomes after aortic valve replacement for aortic insufficiency.
Methods |
All consecutive adult patients who underwent bioprosthetic aortic valve replacement for aortic insufficiency at two European centres (in France and Germany) between May 2005 and December 2020 were analysed.
Results |
During the study period, 289 patients were included. Mean age was 56.9±12.5 years. Overall operative mortality was 1.5%, and the 10-year survival estimate rate was 75.0%, which was significantly lower than in the age- and sex-matched general population, with a standardized mortality ratio of 2.88 (95% confidence interval 1.96–4.08; P<0001). Freedom from aortic valve-related death was 87.6%, and from aortic valve-related reoperation was 87.4%. No patient aged>60 years was reoperated on during follow-up. Freedom from severe structural valve deterioration at 10 years was 73.3%, and freedom from moderate structural valve deterioration at 10 years was 50.3%. Freedom from major adverse valve-related events at 10 years was 69.7%.
Conclusions |
Although bioprosthetic aortic valve replacement for aortic insufficiency shows good early results, 10-year mortality and major adverse valve-related event rates in young patients may be a concern, with a reduction in life expectancy compared with the general population.
Le texte complet de cet article est disponible en PDF.Keywords : Aortic valve replacement, Aortic insufficiency, Bioprosthesis
Abbreviations : AI, AVR, MAVRE, SVD
Plan
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Vol 115 - N° 11
P. 588-597 - novembre 2022 Retour au numéro
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