Monkeypox virus productively infects human induced pluripotent stem cell-derived astrocytes and neural progenitor cells - 29/11/22
Doi : 10.1016/j.jinf.2022.10.016
Thanathom Chailangkarn a, ⁎ 
, Samaporn Teeravechyan a, Khemphitcha Attasombat a, Theeradej Thaweerattanasinp a, Kitpong Sunchatawirul b, Pawita Suwanwattana b, Krit Pongpirul c, Anan Jongkaewwattana a
, Samaporn Teeravechyan a, Khemphitcha Attasombat a, Theeradej Thaweerattanasinp a, Kitpong Sunchatawirul b, Pawita Suwanwattana b, Krit Pongpirul c, Anan Jongkaewwattana a a Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), 113 Thailand Science Park, Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani 12120, Thailand
b Department of Disease Control, Ministry of Public Health, Bamrasnaradura Infectious Diseases Institute, Nonthaburi 11000, Thailand
c Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
⁎Corresponding author.
Highlights |
• | MPXV could infect hiPSC-derived astrocytes and NPCs but not neurons. |
• | Only MPXV-infected astrocytes form syncytia. |
• | Similar to Vero, permissive cell line, MPXV can replicate in astrocytes and NPCs. |
Plan
© 2022
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 85 - N° 6
P. 702-769 - décembre 2022 Retour au numéro
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