State-of-the-art cerium nanoparticles as promising agents against human viral infections - 15/11/22

Doi : 10.1016/j.biopha.2022.113868

Milad Zandi ^a,^{^{1
Milad Zandi and Fatemeh Hosseini contributed equally as co-first authors.}}, Fatemeh Hosseini ^b,^c,^{^{1
Milad Zandi and Fatemeh Hosseini contributed equally as co-first authors.}}, Ahmad Hosseinzadeh Adli ^a,^d, Shokrollah Salmanzadeh ^e, Emad Behboudi ^f, Peyman Halvaei ^c, Ayda Khosravi ^g, Samaneh Abbasi ^h,^⁎
^a Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
^b Department of applied Cell Sciences, School of Advanced Technologies on Medicine, Tehran University of Medical Sciences, Tehran, Iran
^c Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies on Medicine, Tehran University of Medical Sciences, Tehran, Iran
^d Department of Bacteriology and Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
^e Infectious and tropical diseases research center, Health research institute, Faculty of medicine, Ahvaz Jundishapur University of medical sciences, Iran
^f Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
^g Experimental Medicine Research Center, Tehran University of Medical Sciences, Iran
^h Department of Microbiology, Faculty of Medicine, Abadan University of Medical Sciences, Abadan, Iran

^⁎Corresponding author.

Abstract

The world is faces a significant global health challenge in the form of viral infections, particularly the emergence of viral strains that are resistant to effective antiviral therapies. This underscores the urgent need for the development of effective and safe antiviral agents. Nanoscale materials are now being used as novel antiviral agents. Cerium nanoparticles have unique chemical and physical properties that make them particularly promising for viral infections. These particles reduce inflammation and the autoimmune response. Cerium nanoparticles, in addition to their antiviral properties, have many other advantages that are highly sought after for various aspects of biomedical applications. This review focuses on the various properties of cerium nanoparticles as a novel agent against viral infections.

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Keywords : Cerium nanoparticle, Adjuvant, Vaccine, Viral Infections

Plan

Introduction

The role of metal nanoparticles in infectious diseases

Cerium nanoparticle

Cerium nanoparticle and immune responses

Cerium nanoparticle & viral infection

Challenges and future directions of cerium nanoparticles in medicine

Conclusion

Ethics approval

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State-of-the-art cerium nanoparticles as promising agents against human viral infections - 15/11/22

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