The intravenous vancomycin prescription practices of French infectious disease specialists: A cross-sectional observational study - 22/10/22
Highlights |
• | Infectious Disease specialists generally prescribe vancomycin by continuous administration, preceded by a loading dose. |
• | Evaluation of co-administrations, dedicated venous access, and choice of catheter for prolonged treatment are not routine. |
• | Our results suggest an imperative need to improve the modalities of intravenous vancomycin administration. |
Abstract |
Introduction |
Vancomycin prescription modalities remain non-consensual. We examined and evaluated the vancomycin prescription habits of infectious disease specialists in France.
Methods |
Through an anonymized online questionnaire sent to members of the French Infectious Diseases Society, detailed information on vancomycin prescription modalities was collected.
Results |
Out of the 712 physicians contacted, 179 (25%) completed the questionnaire; 174 (97%) of them routinely prescribed intravenous vancomycin: 95 (55%) by continuous infusion only, 12 (7%) by intermittent infusion, while 67 (38%) used the two modalities.
Among continuous administration users, 157 (97%) applied a loading dose of 15 mg/kg or less (n = 80, 49%), 20–25 mg/kg (n = 33, 20%), or 30 mg/kg or more (n = 45, 28%); 143 (88%) used a maintenance dosage of 30 mg/kg/day and 157 (97%) carried out drug monitoring.
Conclusion |
In France, infectious disease specialists favor continuous administration of vancomycin using a loading dose, with systematic monitoring of vancomycin serum concentrations.
Le texte complet de cet article est disponible en PDF.Keywords : Clinical practice, Loading dose, Vancomycin
Plan
Vol 52 - N° 7
P. 414-417 - octobre 2022 Retour au numéro
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