Clinical outcomes of digital health in adults with cystic fibrosis - 23/09/22
, Paola Iacotucci a, 1 , Dandi Qiao b , Lorenza Ferrillo a , Jolanda Somma a , Serena Buonaurio a , Marcella d’Ippolito a , Assunta Celardo a , Daniela Savi c, ⁎ Abstract |
Background |
The aim of this study was to assess the long-term clinical impact of the application of e-health as part of a virtual model of care in patients with Cystic Fibrosis (CF).
Methods |
Digital care group (DCG) were deemed suitable for using the NuvoAir Home platform to monitor their disease at home as part of a virtual model of care project. The usual care group (UCG) remained on usual care. NuvoAir Home platform consists of a smartphone application, Bluetooth spirometer and a clinician portal. Data on pulmonary function, Cystic Fibrosis Questionnaire–Revised (CFQR) and pulmonary exacerbations were collected at baseline and after twelve months. A survey for the digital care group was emailed to evaluate their experience using the technology.
Results |
Between February 2020 and May 2020 a cohort of 43 CF patients were recruited for the DCG (26 females; mean age 31.6 ± 6.8; 16 homozygous for delta F508; FEV1 48.4 ± 16.3% predicted) and 36 CF patients for UCG (18 females; mean age 29.1 ± 9.4; 6 homozygous for delta F508; FEV1 77.0 ± 25.0% predicted). CFQ-R score improved significantly through 12 months in the DCG with a mean change of 13.8 points, p < 0.0001, and no changes for the UCG (p = 0.73). When we analyzed the subgroup of CF patients on digital and usual care who did not receive CFTR modulator therapy, we found a change in CFQ-R score which was significantly associated with the use of digital technology while adjusting for baseline differences (p = 0.020). There was no significant difference in the change in lung function and number of exacerbations. 90% of patients reported they understood their CF better using the NuvoAir Home platform. No changes in medical treatment were reported during that time.
Conclusions |
The application of digital technologies in the management of adults with CF showed an improvement in patients’ quality of life. Using a virtual model of care was well accepted by CF patients and improved their understanding of their medical condition.
Le texte complet de cet article est disponible en PDF.Highlights |
• | It is important to assess clinical effects provided by the application of e-health in CF. |
• | Digital technologies in CF showed an improvement in patients' quality of life. |
• | The virtual model was well accepted, enabling patients to understand trends in their health status. |
• | The virtual model supported clinician and patient confidence in decision making. |
• | Our results will help clinicians to plan future directions for CF management. |
Keywords : Cystic fibrosis, Digital health, Longer-term telehealth benefits, Virtual monitoring
Abbreviations : CF, BMI, FEV1, CFQ-R, pwCF
Plan
Vol 202
Article 106970- octobre 2022 Retour au numéro
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