Routine Use of Cerebral Magnetic Resonance Imaging in Infants Born Extremely Preterm - 15/09/22
Abstract |
Objective |
To describe cerebral abnormalities and their risk factors in a contemporary cohort of infants born extremely premature after the introduction of routine cerebral magnetic resonance imaging (cMRI) at term-equivalent age.
Study design |
All cMRI examinations performed during November 2017 and November 2020, based on a standardized neonatal cMRI protocol, were included into analysis. Pathologies were retrospectively classified into 3 categories: intraventricular hemorrhage (IVH), white matter disease, and cerebellar injuries.
Results |
A total of 198 cMRI examinations were available for analyses; 93 (47%) showed abnormalities, most frequently IVH (n = 65, 33%), followed by cerebellar injuries (n = 41, 21%), and white matter disease (n = 28, 14%). Severe abnormalities were found in 18% of patients (n = 36). Significant clinical risk factors for abnormalities on cMRI were lower Apgar scores, lower umbilical artery and first neonatal pH, asphyxia, blood culture–proven sepsis (especially late-onset), and prolonged need of respiratory support and supplemental oxygen.
Conclusions |
After routine cMRI, without preconfirmed pathology by cranial ultrasonography, low-grade IVH, noncystic white matter disease, and cerebellar injuries were the most frequently found abnormalities. The clinical value and long-term benefit of the detection of these low-grade pathologies have yet to be confirmed.
Le texte complet de cet article est disponible en PDF.Keywords : newborn, preterm infant, neuroimaging, neonatal neurology, neonatal brain
Abbreviations : BPD, cMRI, cPVL, CUS, IVH, pHneon, pHumb, SWI, TEA
Plan
| The authors declare no conflicts of interest. |
Vol 248
P. 74 - septembre 2022 Retour au numéro
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