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Childhood Violence Exposure Predicts High Blood Pressure in Black American Young Adults - 15/09/22

Doi : 10.1016/j.jpeds.2022.05.039 
Gaurav Kapur, MD 1, 2, , Anaïs F. Stenson, PhD 3, , Lisa M. Chiodo, PhD 4, Virginia Delaney-Black, MD, MPH 1, John H. Hannigan, PhD 5, 6, 7, 8, 9, James Janisse, PhD 10, Hilary H. Ratner, PhD 7, 9
1 Department of Pediatrics, Wayne State University, Detroit, MI 
2 Department of Pediatrics, Central Michigan University, Mount Pleasant, MI 
3 Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 
4 College of Nursing, University of Massachusetts–Amherst, Amherst, MA 
5 Department of Obstetrics & Gynecology, Wayne State University, Detroit, MI 
6 C.S. Mott Center for Human Growth & Development, Wayne State University, Detroit, MI 
7 Merrill-Palmer Skillman Institute for Child & Family Development, Wayne State University, Detroit, MI 
8 Center for Urban Responses to Environmental Stressors, Wayne State University, Detroit, MI 
9 Department of Psychology, Wayne State University, Detroit, MI 
10 Department of Family Medicine & Public Health Sciences, Wayne State University, Detroit, MI 

Reprint requests: Anaïs F. Stenson, PhD, Wayne State University School of Medicine, Tolan Park Medical Building, Suite 2C, 3901 Chrysler Service Drive, Detroit, MI 48201Wayne State University School of MedicineTolan Park Medical BuildingSuite 2C3901 Chrysler Service DriveDetroitMI48201

Abstract

Objective

To test the impact of childhood adversity, including community violence exposure, on hypertension risk in Black American young adults to understand what risk factors (eg, prenatal factors, later exposures) and ages of adversity exposure increased hypertension risk.

Study design

The study included 396 Black American participants with data from prenatal, birth, and age 7-, 14-, and 19-year visits. At age 19 years, individuals with blood pressure (BP) measures >120 mmHg systolic and/or >80 mmHg diastolic were classified as having high blood pressure (HBP), and those with BP <120/80 mmHg were classified as normal. Associations between prenatal and birth risk factors; childhood adversity at age 7, 14, and 19 years; age 19 body mass index (BMI); and both systolic and diastolic BP at age 19 were tested using logistic regression models.

Results

Age 19 BMI was positively associated with systolic and diastolic HBP status at age 19. Controlling for all covariates, community violence exposure at age 7 and 19 years was associated with 2.2-fold (95% CI, 1.242-3.859) and 2.0-fold (95% CI, 1.052-3.664) greater odds of systolic HBP, respectively, at age 19 years. Prenatal risk, birth risk, and other dimensions of childhood adversity were not associated with HBP in this cohort.

Conclusion

Childhood community violence exposure is a significant risk factor for HBP in young adults. As Black American children typically experience more community violence exposure than other American children, our results suggest that racial disparities in childhood community violence exposure may contribute to racial disparities in adult hypertension burden.

Le texte complet de cet article est disponible en PDF.

Keywords : blood pressure, hypertension, adverse childhood experiences, childhood violence exposure, developmental origins of health and disease

Abbreviations : ACE, BP, BMI, CREV, HBP, SCECV, SCHOO-BE, SES, SNS, SRSS, TISH


Plan


 This study was supported by funding from the National Institute on Drug Abuse (Grants R01 DA08524 and R01 DA016373), the US Department of Education’s Cognition and Student Learning Program (GrantR30 5H020035), the Blue Cross Blue Shield of Michigan Foundation (Grant 2206.II), and the National Institute of Environmental Health Sciences (Grant P30 ES020957). The authors declare no conflicts of interest.


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Vol 248

P. 21 - septembre 2022 Retour au numéro
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