Inhaled sedation in the intensive care unit - 10/09/22
Abstract |
Inhaled sedation with halogenated agents, such as isoflurane or sevoflurane, is now feasible in intensive care unit (ICU) patients through dedicated vaporisers and scavenging systems. Such a sedation strategy requires specific equipment and adequate training of ICU teams. Isoflurane and sevoflurane have ideal pharmacological properties that allow efficient, well-tolerated, and titratable light-to-deep sedation. In addition to their function as sedative agents, these molecules may have clinical benefits that could be especially relevant to ICU patients. Our goal was to summarise the pharmacological basis and practical aspects of inhaled ICU sedation, review the available evidence supporting inhaled sedation as a viable alternative to intravenous sedation, and discuss the remaining areas of uncertainty and future perspectives of development.
Le texte complet de cet article est disponible en PDF.Keywords : inhaled sedation, isoflurane, sevoflurane, intensive care unit, acute respiratory distress syndrome
Plan
Vol 41 - N° 5
Article 101133- octobre 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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