Chronic respiratory rhinitis: Toward endoscopic diagnosis of nasal allergy? An observational study - 01/09/22

Doi : 10.1016/j.anorl.2022.02.002

M. Barron ^a, D.-T. Nguyen ^a,^b, C. Rumeau ^a,^c, R. Jankowski ^a,^c,^⁎
^a Service ORL, université de Lorraine, CHRU de Nancy, 54000 Nancy, France
^b Université de Lorraine, Inserm, IADI, 54000 Nancy, France
^c Université de Lorraine, DevAH, 54000 Nancy, France

^⁎Corresponding author at: Service d’oto-rhino-laryngologie et chirurgie cervico-faciale, CHRU de Nancy, 5, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.Service d’oto-rhino-laryngologie et chirurgie cervico-faciale, CHRU de Nancy5, rue du MorvanVandoeuvre-les-Nancy54500France

Abstract

Objective

The study objective was to assess the functional, endoscopic and tomodensitometric semiology of a cohort of patients with chronic respiratory rhinitis (CRR). The concept of CRR is based on the anatomical, pathophysiological and semiological individualization of the respiratory nose within the sinonasal organ, in which three noses are distinguished by the parallel study of evolution and development in the “evo-devo” theory of the origins of the nose, anterior base of the skull and middle third of the face.

Material and method

A single-center retrospective study included a cohort of 28 patients (16 men and 12 women, aged 19 to 69years) with CRR. The main objective was to describe symptoms clinically, endoscopically and on CT. The secondary objective was to compare clinical symptomatology and CT data between CRR and a control group of 31 patients with nasal polyposis (NP). The endoscopic semiology of CRR was analyzed consensually on video recordings using a pre-established grid. The DyNaChron self-administered questionnaire was used to compare symptom intensity and deterioration in quality of life. Olfaction was compared using the Sniffin’ Sticks test. CT opacities were compared between CRR and NP on Lund-Mackay sinus score and a specific ethmoid opacities score.

Results

In CRR, endoscopy found a constant association of inflammatory or edematous signs in the inferior or middle turbinates with signs of hypersecretion. Ethmoid opacities in CRR were discrete and significantly smaller than in NP (P<0.0001), and were mainly located in the medial compartment in contact with the olfactory cleft (P<0.0001). Allergological assessment was positive in 17 of the 28 cases of CRR. Chronic nasal dysfunction was similar in CRR and NP, but olfactory impairment was significantly lower in CRR (P<0.0001).

Conclusion

The CRR entity clinically resembles atopic central compartment disease. In both entities, endoscopy reveals inflammatory lesions restricted to the nasal cavities without significant ethmoid opacity on CT, an observation which seems to contradict the pathophysiological united airway concept.

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Keywords : Chronic rhinitis, Allergic rhinitis, Sinus CT, Quality of life questionnaire