Long-acting HIV fusion inhibitor albuvirtide combined with ritonavir-boosted lopinavir for HIV-1-infected patients after failing the first-line antiretroviral therapy: 48-week randomized, controlled, phase 3 non-inferiority TALENT study - 30/07/22

Bin Su ^a, #

  These authors contributed equally to this work.

, Cheng Yao ^b, #

  These authors contributed equally to this work.

, Qing-Xia Zhao ^c, #

  These authors contributed equally to this work.

, Wei-Ping Cai ^d, #

  These authors contributed equally to this work.

, Min Wang ^e, #

  These authors contributed equally to this work.

, Hong-Zhou Lu ^f, #

  These authors contributed equally to this work.

, Ting-Ting Mu ^a, #

  These authors contributed equally to this work.

, Yuan-Yuan Chen ^c, Li Liu ^f, Hui Wang ^g, Yun He ^g, Yu-Huang Zheng ^h, Ling-Hua Li ^d, Jin-Feng Chen ^d, Jian-Hua Yu ⁱ, Biao Zhu ^j, Min Zhao ^k, Yong-Tao Sun ^l, Wen-Hui Lun ^m, Yi-Hang Zhang ^a, Hu Wang ^a, Wei Xia ^a, Li-Jun Sun ^a, Li-Li Dai ^a, Tai-Yi Jiang ^a, Mei-Xia Wang ^a, Qing-Shan Zheng ⁿ, Hai-Yan Peng ^o, Yao Wang ^o, Min Hu ^b, Xia Liu ^b, Rong-Jian Lu ^b, Jian-Hua Hu ^b, Cheng-Chen Sun ^b, Hui Xing ^p, Yi-Ming Shao ^p, Dong Xie ^{b, ⁎} , Tong Zhang ^{a, ⁎} , Fu-Jie Zhang ^{m, ⁎} , Hao Wu ^a, †

  For the TALENT Study Team

, ^⁎

^a Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China 

^b Frontier Biotechnologies Inc., Nanjing, Jiangsu 211122, China 

^c Department of Infectious Diseases, Infectious Disease Hospital of Henan Province, Zhengzhou, Henan 450061, China 

^d Infectious Disease Center, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510060, China 

^e Institute of HIV/AIDS, the First Hospital of Changsha, Changsha, Hunan 410005, China 

^f Department of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China 

^g Department of Infectious Diseases, National Clinical Center for Infectious Diseases, Shenzhen Third People's Hospital, Shenzhen, Guangdong 518112, China 

^h Department of Infectious Diseases, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China 

ⁱ Department of Infectious Diseases, Xixi Hospital of Hangzhou, Hangzhou, Zhejiang 310023, China 

^j State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang 310003, China 

^k National Clinical Research Center for Infectious Diseases, the Fifth Medical Center of PLA General Hospital, Beijing 100039, China 

^l Department of Infectious Diseases, Tangdu Hospital, the Fourth Military Medical University, Xi'an Shaanxi 710038, China 

^m Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China 

ⁿ Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China 

^o Beijing Co-CRO Medical Development Co., Ltd., Beijing 100711, China 

^p State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China 

^⁎Corresponding authors.