Plasma cell-rich acute rejection after living donor liver transplantation: Unusual or underestimated diagnosis? - 29/07/22

Doi : 10.1016/j.liver.2022.100108

I.F. Montasser ^a,^⁎,^{^{1
These authors contributed equally to this work.}} , H. Ebada ^a,^{^{1
These authors contributed equally to this work.}}, H Faheem ^b,^{^{1
These authors contributed equally to this work.}}, H Dabbous ^a,^{^{1
These authors contributed equally to this work.}}, Y. Massoud ^a,^{^{1
These authors contributed equally to this work.}}, M. Salah ^a,^{^{1
These authors contributed equally to this work.}}, M. Sakr ^a,^{^{1
These authors contributed equally to this work.}}, M. Bahaa ^c,^{^{1
These authors contributed equally to this work.}}, M El Monayeri ^d,^{^{1
These authors contributed equally to this work.}}, M.El Meteini ^c,^{^{1
These authors contributed equally to this work.}}
^a Department of Tropical Medicine, Ain Shams Centre for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt
^b Department of Internal Medicine, Ain Shams Centre for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt
^c Department of Hepatobiliary Surgery & Liver Transplantation, Ain Shams Centre for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt
^d Department of Pathology, Ain Shams Centre for Organ Transplantation (ASCOT), Ain Shams University, Cairo, Egypt

^⁎Corresponding author.

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Abstract

The term plasma cell-rich rejection (PCRR) was recently used to replace that of de novo autoimmune hepatitis by the 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology, which introduced the notion of Antibody-Mediated Rejection. However, the clear pathophysiology and actual incidence of plasma cell-rich acute rejection after liver transplantation remain unclear and need further investigation. Here, we report a case of plasma cell-rich rejection after living donor liver transplantation (LDLT) with an adequate response to pulse steroids.

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Keywords : Plasma cell- rich rejection, Liver transplantation, De novo autoimmune hepatitis

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Article 100108- octobre 2022 Retour au numéro

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Plasma cell-rich acute rejection after living donor liver transplantation: Unusual or underestimated diagnosis? - 29/07/22

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