Methylene blue in combination with sunlight as a low cost and effective disinfection method for coronavirus-contaminated PPE - 28/07/22
Doi : 10.1016/j.ajic.2022.02.019
Kevin A. Vos, PhD a, Paul M.K. Gordon, PhD b, Belinda Heyne, PhD a, ⁎ 
a Chemistry Department, University of Calgary, Calgary, Alberta, Canada
b CSM Centre for Health Genomics and Informatics, University of Calgary, Calgary, Alberta, Canada
⁎Address correspondence to Belinda Heyne, PhD, Chemistry Department, University of Calgary, Calgary, Alberta, 2500 University Dr, NW, T2N 1N4 Canada.Chemistry DepartmentUniversity of CalgaryUniversity Dr, NW, T2N 1N4CalgaryAlberta2500Canada
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Highlights |
• | Methylene blue exposed to sunlight inactivates MHV virus in solution. |
• | Methylene blue exposed to sunlight inactivates MHV on mask materials in less than 5 minutes.. |
• | Genetic damage suggests applicability of this decontamination method to other viruses. |
Abstract |
Using the Murine Hepatitis Virus (MHV) A59 coronavirus as a SARS-CoV-2 animal surrogate, we validated that methylene blue (MB) in combination with sunlight exposure is a robust, fast, and low-cost decontamination method for PPE that should be added to the toolbox of practical pandemic preparedness.
Le texte complet de cet article est disponible en PDF.Key Words : Decontamination, Photochemistry, Next generation sequencing, Murine hapatitis virus, Pandemic preparedness
Plan
| Funding/Support: The authors acknowledge that funds for the project were provided by WHO based on a grant from the German Federal Ministry of Health (BMG). This work has been supported in part by the Natural Sciences and Engineering Research Council (NSERC) of Canada. BH acknowledges NSERC of Canada Discovery Grant (RGPIN/03824-2017) for funding. Open access of this article is sponsored by the World Health Organization. |
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| Conflict of interest: The authors declare no conflict of interest. |
© 2022
Publié par Elsevier Masson SAS.
Vol 50 - N° 8
P. 906-908 - août 2022 Retour au numéro
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