An updated review of the methods, guidelines of, and controversies on screening for colorectal cancer - 20/06/22
Abstract |
Background |
Screening for early detection of colorectal cancer (CRC), adenomatous polyps, and precancerous lesions can reduce mortality. This review aimed to illustrate methods, guidelines, and clinical utility of CRC screening programs.
Methods |
Literature search of PubMed and Scopus electronic databases was independently performed by two authors in September 2021. Articles discussing CRC screening methods and updated guidelines were reviewed.
Results |
After reviewing the full text of 55 studies, it was found that the screening tests for CRC are divided into stool-based, endoscopic, and molecular. All CRC screening guidelines recommend screening starting at age 45–50, but vary regarding screening methods, frequency, and timing of screening discontinuation. Controversies include clinical benefits of screening the elderly and discontinuation of screening. Effective screening barriers involve patient- and healthcare-related factors.
Conclusion |
Overall, screening should start at age 45–50 for average-risk individuals. Colonoscopy and FIT tests are standard modalities recommended for regular screening. Increasing public awareness of the importance of screening and implementing mass national screening programs can detect early CRC and decrease related mortality.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Screening can be done by stool-based tests, endoscopic tests, and molecular tests. |
• | Different CRC screening guidelines exist. |
• | Guidelines vary in relative to the preferred method of screening and age at which to start screening. |
• | Clinical value of screening in the elderly is controversial. |
• | The ideal screening method has not been universally accepted. |
• | There are patient-related and health care system-related barriers to efficient screening. |
Keywords : Colorectal cancer, Screening, Review, CRC, Comprehensive
Plan
Vol 224 - N° 1PB
P. 339-347 - juillet 2022 Retour au numéro
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