Vaccine Ab neutralization against Omicron and SARS-CoV-2 variants using neutralization and specific ELISA assays - 20/05/22
Doi : 10.1016/j.jinf.2022.02.031
Valentine Marie Ferré, Samuel Lebourgeois, Houssem Redha Chenane, Reyene Menidjel, Christelle Masson, Gilles Collin, Benoit Visseaux, Diane Descamps, Nadhira Fidouh, Charlotte Charpentier ⁎ 
Service de Virologie, Université de Paris, INSERM, IAME, UMR 1137, AP-HP, Hôpital Bichat-Claude Bernard, 46 Rue Henri Huchard, Paris F-75018, France
⁎Corresponding author.
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Highlights |
• | Omicron neutralization titers were in median 16- and 8-fold lower than for Delta. |
• | High correlation between two pseudoneutralization assays was observed. |
• | High correlation between a pseudoneutralization and a VOC-specific ELISA. |
• | Omicron had the lowest titers by neutralization and by variant-specific ELISA assay. |
Keywords : SARS-CoV-2, Vaccine antibodies, Neutralization, Omicron, Humoral response
Plan
© 2022
Publié par Elsevier Masson SAS.
Vol 84 - N° 6
P. 834-872 - juin 2022 Retour au numéro
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