Acetaminophen and Xenobiotic Metabolites in Human Milk and the Development of Bronchopulmonary Dysplasia and Retinopathy of Prematurity in a Cohort of Extremely Preterm Infants - 06/05/22
Abstract |
This retrospective cohort study sought to identify the association between certain xenobiotic metabolites in maternal breast milk and the diagnoses of bronchopulmonary dysplasia and retinopathy of prematurity in extremely preterm infants. Several acetaminophen metabolites were associated with a 3- to 6-fold increased odds of these disorders, and metabolites of certain food products, benzoate, and caffeine were associated with decreased odds.
Le texte complet de cet article est disponible en PDF.Keywords : bronchopulmonsary dysplasia, preterm infant, acetaminophen, breast milk, xenobiotics
Abbreviations : BPD, NEC, PDA, ROP, SNAP
Plan
| K.S. received funding support from the (Grant T32 National Institute of Child Health and Human Development 098061) for completion of this project. C.M. serves on the scientific advisory boards of LactaLogics and Plakous Therapeutics. C.M. has received research funding from the Mead Johnson Foundation. None of these entities had any role in the conduct of this study. The other authors declare no conflicts of interest. |
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| Presented as an oral abstract at the American Academy of Pediatrics Perinatal and Developmental Medicine Symposium Virtual Conference, November 10-12, 2020. |
Vol 244
P. 224 - mai 2022 Retour au numéro
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