Meta-analysis of immunologic response after COVID-19 mRNA vaccination in solid organ transplant recipients - 05/05/22
Doi : 10.1016/j.jinf.2022.02.016
Kefu Tang a, ⁎ 
, Xi Wu b, Ying Luo a, Zhiying Wei c, Liyun Feng a, Lei Wu a
, Xi Wu b, Ying Luo a, Zhiying Wei c, Liyun Feng a, Lei Wu a a Prenatal Diagnosis Center, Department of Clinical Laboratory, Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China
b Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China
c Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
⁎Corresponding author.
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Highlights |
• | Impaired humoral and cellular immunity after COVID-19 vaccination in SOTRs was found. |
• | The seropositivity rate increased with the doses of mRNA vaccination in SOTRs. |
• | The seropositivity varies across different type of organ transplant recipients. |
• | Antimetabolite and belatacept therapy was associated with IgG seronegativity. |
• | COVID-19 mRNA vaccines are safe and well-tolerated in SOTRs. |
Keywords : COVID-19, Solid organ transplant recipients, mRNA vaccine, Immunologic response
Plan
© 2022
Publié par Elsevier Masson SAS.
Vol 84 - N° 5
P. e73-e75 - mai 2022 Retour au numéro
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