The high expression of key components of inflammasome and pyroptosis might lead to severe COVID‐19 infection in cancer patients - 08/04/22
Doi : 10.1016/j.jinf.2022.01.043
Haoran Cui a, b, c, Jiaxin Liu b, c, Leiliang Zhang a, b, c, ⁎ 
a Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China
b Department of Pathogen Biology, School of Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
c Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
⁎Corresponding author. Leiliang Zhang, Department of Pathogen Biology, School of Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.Department of Pathogen BiologySchool of Basic Medical SciencesShandong First Medical University & Shandong Academy of Medical SciencesJinanShandongChina
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Highlights |
• | ● Some NLRP3-inflammasome/pyroptosis components are highly expression in cancer patients. |
• | ● The expression levels of ASC were up-regulated in all cancer type we examined. |
• | ● All five NLRP3-inflammasome/pyroptosis components were up-regulated in LAML and PAAD. |
© 2022
Publié par Elsevier Masson SAS.
Vol 84 - N° 4
P. e19-e21 - avril 2022 Retour au numéro
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