Contrasting specific antibody response to BNT162b2 mRNA vaccination in SARS-CoV-2-naive and previously infected nursing home residents - 02/03/22
Doi : 10.1016/j.jinf.2021.10.011
Yong Chong a, ⁎ 
, Naoki Tani a, Takeyuki Goto a, Akiko Yonekawa a, Hideyuki Ikematsu b, Nobuyuki Shimono c, Yosuke Tanaka d, Koichi Akashi a
, Naoki Tani a, Takeyuki Goto a, Akiko Yonekawa a, Hideyuki Ikematsu b, Nobuyuki Shimono c, Yosuke Tanaka d, Koichi Akashi a a Medicine and Biosystemic Science, (The First Department of Internal Medicine), Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582, Japan
b Japan Physicians Association, Tokyo, Japan
c Center for the Study of Global Infection, Kyushu University Hospital, Fukuoka, Japan
d Medical Corporation SOUSEIKAI, Kanenokuma Hospital, Fukuoka, Japan
⁎Corresponding author.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Highlights |
• | Antibody responses to SARS-CoV-2 vaccination were examined in nursing home residents. |
• | Anti-spike IgG levels after two doses were extremely lower in SARS-CoV-2-naive residents than in healthcare workers. |
• | Previously infected residents obtained rapid and robust antibody responses even after one dose. |
• | Increasing age did not result in reduced IgG levels in previously infected residents and healthcare workers. |
• | The pronounced responses in previously infected residents were observed even more than one year after infection. |
© 2021
Publié par Elsevier Masson SAS.
Vol 84 - N° 3
P. 418-467 - mars 2022 Retour au numéro
Article précédent
- High compliance to infection control measures prevented guest-to-staff transmission in COVID-19 quarantine hotels
- Xin Li, Hong Chen, Lu Lu, Lin-Lei Chen, Brian Pui-Chun Chan, Shuk-Ching Wong, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Kwok-Hung Chan, Kelvin Kai-Wang To
- Persistence at one year of neutralizing antibodies after SARS-CoV-2 infection: Influence of initial severity and steroid use
- Olivier Epaulard, Marlyse Buisson, Benjamin Nemoz, Marion Le Maréchal, Nicolas Terzi, Jean-François Payen, Marie Froidure, Myriam Blanc, Anne-Laure Mounayar, Fanny Quénard, Isabelle Pierre, Patricia Pavese, Raphaele Germi, Laurence Grossi, Sylvie Larrat, Pascal Poignard, Julien Lupo
Bienvenue sur EM-consulte, la référence des professionnels de santé.