MRI characteristics of intralabyrinthine schwannoma on post-contrast 4 h-delayed 3D-FLAIR imaging - 24/02/22
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Highlights |
• | Magnetic resonance imaging has a critical role in the diagnosis of intralabyrinthine schwannoma. |
• | Intralabyrinthine schwannoma can mimic endolymphatic hydrops on post-contrast three-dimensional FLAIR images. |
• | When performing “hydrops protocol” MRI for cochleovestibular disorders, differentiation between intralabyrinthine schwannoma and endolymphatic hydrops requires analysis of T2-weighted images. |
Abstract |
Purpose |
The purpose of this study was to describe the MRI characteristics of intralabyrinthine schwannoma (ILS) on post contrast three-dimensional (3D) fluid-attenuation-inversion-recovery (FLAIR) images obtained four hours after intravenous administration of a gadolinium-based contrast agent (4h-3D-FLAIR).
Materials and methods |
This IRB-approved retrospective multi-center study included patients presenting with typical ILS from January 2016 to October 2020. All medical charts were systematically collected. All MRI examinations, including 4h-3D-FLAIR images, were reviewed by two board-certified neuroradiologists. Main outcome measures were location, signal intensity and associated anomalies of ILS.
Results |
Twenty-seven out of 8730 patients (0.31%) referred for the investigation of a cochleovestibular disorder had a final diagnosis of ILS. There were 13 men and 14 women with a mean age of 52 ± 17 (SD) years (age range: 20–86 years). The most common clinical presentation was unilateral progressive sensorineural hearing loss (16/27; 59%). All ILS were unilateral and 15 (15/27; 55%) were intracochlear. All ILS presented as a hypointense filling defect within the labyrinth on T2-weighted images that enhanced on post-contrast T1-weighted images. On 4h-3D-FLAIR images, all ILS presented as a hypointense filling defect, associated with diffuse perilymphatic hyperintensity. Two patients (2/27; 7%) presented with ipsilateral endolymphatic hydrops.
Conclusion |
ILS displays consistent features on post-contrast 4h-3D-FLAIR images. ILS should not be confused with endolymphatic hydrops and requires a systematic analysis of the corresponding T2-weighted images.
Le texte complet de cet article est disponible en PDF.Index terms : Magnetic resonance imaging, Intralabyrinthine schwannoma, 4h-delayed 3d flair, Endolymphatic hydrops, Imaging, Three dimensional
Abbreviations : 3D, 4h-3D-FLAIR, EH, FOV, FLAIR, ILS, MRI, Nex, SD, TE, TI, TR
Plan
Vol 103 - N° 3
P. 171-176 - mars 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.