Nephron-Sparing Approach For Familial Bilateral Synchronous Wilms Tumors - 22/02/22

Doi : 10.1016/j.urology.2021.10.022

Victoria Turnbull ¹, Harkanwal Randhawa ², Yuding Wang ², Melissa McGrath ³, Luis H. Braga ^1,^2,^3,^4,^⁎
¹ Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada
² Division of Urology, McMaster University, Hamilton, Ontario, Canada
³ McMaster Pediatric Surgery Research Collaborative, Department of Surgery, McMaster University, Hamilton, Ontario, Canada
⁴ Department of Health, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada

^⁎Address correspondence to: Luis H. Braga, M.D., M.Sc., Ph.D., Department of Surgery, McMaster University, 1200 Main Street West, HHS, room 4E19, L8N 3Z5, Hamilton, Ontario, Canada.Department of SurgeryMcMaster University1200 Main Street West, HHS, room 4E19HamiltonOntarioL8N 3Z5Canada

Abstract

Wilms tumors are the most common renal malignancy of childhood, often presenting as asymptomatic abdominal masses. These tumors can occur either in a unilateral or bilateral fashion, with bilateral tumors more commonly associated with various genetic syndromes and familial inheritance with some known loci. Bilateral tumors present challenges with regards to balancing oncologic control with renal function. Here, we present an unusual case of a young female patient diagnosed with bilateral Wilms tumors on the background of a strong family history and unknown genetic loci.

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Financial Disclosure: The authors declare that they have no relevant financial interests.

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Vol 160

P. 199-202 - février 2022 Retour au numéro

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Nephron-Sparing Approach For Familial Bilateral Synchronous Wilms Tumors - 22/02/22

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