Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients - 12/12/21
Doi : 10.1016/j.jinf.2021.09.012
Andrea Alemany a, b, 1, Pere Millat-Martinez c, 1, Dan Ouchi a, Marc Corbacho-Monné a, Antoni E. Bordoy b, Cristina Esteban b, Águeda Hernández b, Cristina Casañ b, Victoria Gonzalez b, Gèlia Costes a, Mar Capdevila-Jáuregui a, Pamela Torrano-Soler a, Alba San José a, Jordi Ara b, d, Núria Prat d, Bonaventura Clotet a, b, e, Quique Bassat c, f, g, h, i, Montserrat Gimenez b, Ignacio Blanco b, d, Bàrbara Baro c, ⁎ 
, Oriol Mitjà a, b, i
, Oriol Mitjà a, b, i a Fight AIDS and Infectious Diseases Foundation, Badalona, Spain
b Hospital Universitari Germans Trias i Pujol, Barcelona Institute for Global Health, Rosselló, 132, Badalona 08036, Spain
c ISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain
d Gerència Territorial Metropolitana Nord, Institut Català de la Salut, Barcelona, Spain
e Universitat de Vic-Universitat Central de Catalunya (UVIC-UCC), Vic, Spain
f Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique
g ICREA, Pg. Lluís Companys 23, Barcelona 08010, Spain
h Pediatrics Department, Hospital Sant Joan de Déu (University of Barcelona), Barcelona, Spain
i Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain
i Lihir Medical Centre, International SOS Clinic, Lihir Island, Papua New Guinea
⁎Corresponding author.
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Highlights |
• | Self-collected nasal and saliva samples can be used for SARS-CoV-2 screening. |
• | Self-collected nasal and saliva specimens had a 99% and 90% sensitivity, respectively. |
• | Nasopharyngeal swab viral loads correlate better with nasal than saliva. |
• | Viral load correlations are poorer at day 7, when lower viral loads are observed. |
Keywords : SARS-CoV-2, Screening, Saliva, Nasal, Nasopharyngeal swab, Viral load
© 2021
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 83 - N° 6
P. 709-737 - décembre 2021 Retour au numéro
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