Vitamin D supplementation for the treatment of migraine: A meta-analysis of randomized controlled studies - 30/11/21
, Shaoping Wu ⁎ , Yu Zou, Xiaosu QuAbstract |
Introduction |
It is not well established to use vitamin D supplementation for migraine, and this meta-analysis aims to explore the efficacy of vitamin D for migraine patients.
Methods |
PubMed, EMbase, Web of science, EBSCO and Cochrane library databases were systematically searched up to May 2021, and we included randomized controlled trials (RCTs) exploring the effect of vitamin D for migraine patients.
Results |
Six RCTs and 301 patients were included in the meta-analysis. Compared with control group in migraine patients, vitamin D supplementation could remarkably decrease headache attacks per month (MD = −2.74; 95% CI = −3.82 to −1.67; P < 0.00001), headache days per month (MD = −1.56; 95% CI = −2.44 to −0.68; P = 0.0005) and MIDAS score (MD = −5.72; 95% CI = −10.90 to −0.54; P = 0.03), but demonstrated no obvious influence on attack duration (MD = −2.20; 95% CI = −7.38 to 2.97; P = 0.40) or headache severity (MD = −0.56; 95% CI = −1.18 to 0.06; P = 0.08).
Conclusions |
Vitamin D supplementation provided additional benefits to treat migraine.
Le texte complet de cet article est disponible en PDF.Keywords : Vitamin D supplementation, Migraine, Headache attacks per month, Randomized controlled trials
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Vol 50
P. 784-788 - décembre 2021 Retour au numéro
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