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Fascia iliaca block for hip fractures in the emergency department: meta-analysis with trial sequential analysis - 30/11/21

Doi : 10.1016/j.ajem.2021.09.038 
Jeetinder K. Makkar, MD, DNB a, Narinder P. Singh, MD b, , Nidhi Bhatia, MD c, Tanvir Samra, MD d, Preet Mohinder Singh, MD e
a Professor, Department of Anaesthesia and Intensive care, Post Graduate Institute of Medical Education & Research, Chandigarh, India 
b Department of Anaesthesia, MMIMSR, MM (DU), Mullana, Ambala, India 
c Additional Professor, Department of Anaesthesia and Intensive care, Post Graduate Institute of Medical Education & Research, Chandigarh, India 
d Associate Professor, Department of Anaesthesia and Intensive care, Post Graduate Institute of Medical Education & Research, Chandigarh, India 
e Department of Anaesthesia, Washington University in Saint Louis, MO, USA 

Corresponding author at: Department of Anaesthesia, MMIMSR, MM (DU), Mullana, Ambala 133207, India.Department of AnaesthesiaMMIMSRMM (DU)MullanaAmbala133207India

Abstract

Background

Fascia iliaca block (FICB) has been used to reduce pain and its impact on geriatric patients with hip fractures.

Objective

We conducted this meta-analysis to investigate the analgesic efficacy of this block in comparison to standard of care (SOC) when performed by non-anesthesiologist in the emergency department.

Methods

Search on PubMed, SCOPUS, EMBASE, Google Scholar and Cochrane database for randomized and quasi-randomized trials were performed. The primary outcome was to compare pain relief at rest at 2–4 h. The pain relief at various time intervals, reduction in opioid use, the incidence of nausea/ vomiting, delirium and length of hospital stay were the secondary outcomes studied. Trial Sequential Analysis (TSA) was performed for the primary outcome.

Results

Eleven trials comprising 895 patients were included in the meta-analysis. Patients receiving FICB had significant better pain relief at rest at 2–4 h with mean difference of 1.59 (95% CI, 0.59–2.59, p = 0.002) with I2 = 96%. However, the certainty of the evidence was low and TSA showed that the sample size could not reach the requisite information size. A significant difference in pain relief at rest and on movement started within 30 min and lasted till 4 h of the block. Use of FICB was associated with a significant reduction in post-procedure parenteral opioid consumption, nausea and vomiting and length of hospital stay.

Conclusions

FICB is associated with significant pain relief both at rest and on movement lasting up to 4 h as well as a reduction in opioid requirement and associated nausea and vomiting in geriatric patients with hip fracture. However, the quality of evidence is low and additional trials are necessary.

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Highlights

Limited evidence on use of Fascia iliaca compartment block (FICB) in geriatric patientwith hip fracture by non-anesthesiologist
Search on four databases for randomized and quasi randomized trials yielded 11 trials comprising 895 patients.
Resting pain scores at 2–4 h was the primary end point.
FICB is associated with t pain relief lasting up to 4h along withand reduction in opioid requirement

Le texte complet de cet article est disponible en PDF.

Keywords : Fascia iliaca, Analgesia, Hip fracture, Emergency department, Geriatric


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Vol 50

P. 654-660 - décembre 2021 Retour au numéro
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