Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology - 25/11/21
Doi : 10.1016/S1473-3099(21)00191-2
George R Thompson, ProfMD a, b, ⁎ 
, Thuy Le, MD c, d, Ariya Chindamporn, PhD e, Carol A Kauffman, ProfMD f, g, Ana Alastruey-Izquierdo, PhD h, Neil M Ampel, ProfMD i, j, David R Andes, ProfMD k, Darius Armstrong-James, Prof l, Olusola Ayanlowo, ProfMD m, John W Baddley, ProfMD n, Bridget M Barker, ProfPhD o, Leila Lopes Bezerra, ProfPhD p, Maria J Buitrago, ProfPhD h, Leili Chamani-Tabriz, ProfMD q, Jasper F W Chan, ProfMBBS r, s, Methee Chayakulkeeree, ProfMD t, Oliver A Cornely, ProfMD u, v, Cao Cunwei, ProfMD w, Jean-Pierre Gangneux, ProfPhD x, Nelesh P Govender, ProfMD y, z, Ferry Hagen, PhD aa, ab, ac, Mohammad T Hedayati, ProfMD ad, Tobias M Hohl, ProfMD ae, af, Grégory Jouvion, ProfMD ag, ah, Chris Kenyon, ProfPhD ai, Christopher C Kibbler, ProfPhD aj, Nikolai Klimko, ProfMD ak, David C M Kong, ProfMD al, am, Robert Krause, ProfMD an, Low Lee Lee, ProfMD ao, Graeme Meintjes, ProfPhD ap, aq, ar, Marisa H Miceli, MD g, Peter-Michael Rath, ProfMD as, Andrej Spec, MD at, Flavio Queiroz-Telles, ProfMD au, Ebrahim Variava, ProfMBBCh av, Paul E Verweij, ProfMD aw, Ilan S Schwartz, MD ax, Alessandro C Pasqualotto, ProfMD ay, az
, Thuy Le, MD c, d, Ariya Chindamporn, PhD e, Carol A Kauffman, ProfMD f, g, Ana Alastruey-Izquierdo, PhD h, Neil M Ampel, ProfMD i, j, David R Andes, ProfMD k, Darius Armstrong-James, Prof l, Olusola Ayanlowo, ProfMD m, John W Baddley, ProfMD n, Bridget M Barker, ProfPhD o, Leila Lopes Bezerra, ProfPhD p, Maria J Buitrago, ProfPhD h, Leili Chamani-Tabriz, ProfMD q, Jasper F W Chan, ProfMBBS r, s, Methee Chayakulkeeree, ProfMD t, Oliver A Cornely, ProfMD u, v, Cao Cunwei, ProfMD w, Jean-Pierre Gangneux, ProfPhD x, Nelesh P Govender, ProfMD y, z, Ferry Hagen, PhD aa, ab, ac, Mohammad T Hedayati, ProfMD ad, Tobias M Hohl, ProfMD ae, af, Grégory Jouvion, ProfMD ag, ah, Chris Kenyon, ProfPhD ai, Christopher C Kibbler, ProfPhD aj, Nikolai Klimko, ProfMD ak, David C M Kong, ProfMD al, am, Robert Krause, ProfMD an, Low Lee Lee, ProfMD ao, Graeme Meintjes, ProfPhD ap, aq, ar, Marisa H Miceli, MD g, Peter-Michael Rath, ProfMD as, Andrej Spec, MD at, Flavio Queiroz-Telles, ProfMD au, Ebrahim Variava, ProfMBBCh av, Paul E Verweij, ProfMD aw, Ilan S Schwartz, MD ax, Alessandro C Pasqualotto, ProfMD ay, az a Department of Internal Medicine, Division of Infectious Disease, UC Davis Medical Center, Sacramento, CA, USA
b Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA
c Division of Infectious Diseases and International Health, Duke University School of Medicine, Durham, NC, USA
d Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
e Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
f VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
g Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI, USA
h Mycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain
i Division of Infectious Diseases, Mayo Clinic, Phoenix, AZ, USA
j Department of Internal Medicine, Division of Infectious Diseases, University of Arizona College of Medicine, Tucson, AZ, USA
k Department of Internal Medicine, Division of Infectious Diseases, and Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI, USA
l Department of Infectious Diseases, Imperial College London, London, UK
m Department of Medicine, Faculty of Clinical Sciences, University of Lagos, Lagos, Nigeria
n Department of Internal Medicine, Division of Infectious Disease, University of Maryland School of Medicine, Baltimore, MD, USA
o Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ, USA
p Cellular Mycology and Proteomics Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil
q Infectious Diseases Unit, Department of Internal Medicine, Saudi German Hospital Dubai, Dubai, UAE
r State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
s Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
t Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
u Department of Internal Medicine, Excellence Center for Medical Mycology, University Hospital of Cologne, Cologne, Germany
v Department of Internal Medicine, Division of Infectious Diseases, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany
w Department of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
x Department of Internal Medicine, Division of Infectious Diseases, Rennes University, CHU Rennes, Inserm, IRSET-UMR_S 1085, Rennes, France
y National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa
z Department of Internal Medicine, Division of Infectious Diseases, University of the Witwatersrand, Johannesburg, South Africa
aa Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands
ab Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands
ac Laboratory of Medical Mycology, Jining No 1 People’s Hospital, Jining, China
ad Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
ae Infectious Disease Service, Department of Medicine; Memorial Sloan Kettering Cancer Center, New York, NY, USA
af Immunology Program, Sloan Kettering Institute, New York, NY, USA
ag Sorbonne Université, INSERM, Pathophysiology of Pediatric Genetic Diseases, Assistance Publique-Hôpitaux de Paris, Hôpital Armand-Trousseau, UF Génétique Moléculaire, Paris, France
ah Institut Pasteur, Experimental Neuropathology Unit, Paris, France
ai Institute of Tropical Medicine, Antwerp, Belgium
aj Centre for Medical Microbiology, University College London, London, UK
ak Department of Clinical Mycology, Allergy, and Immunology, I Mechnikov North-Western State Medical University, St Petersburg, Russia
al Pharmacy Department, Ballarat Health Services, Ballarat, VIC, Australia
am National Centre for Antimicrobial Stewardship, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
an Section of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Medical University of Graz, Graz, Austria
ao Department of Internal Medicine, Hospital Sultanah Bayiyah, Alor Setar, Kedah, Malaysia
ap Wellcome Centre for Infectious Diseases Research, University of Cape Town, Cape Town, South Africa
aq Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
ar Department of Medicine, University of Cape Town, Cape Town, South Africa
as Institute of Medical Microbiology, University Hospital Essen, Essen, Germany
at Division of Infectious Disease, Washington University School of Medicine, St Louis, MO, USA
au Department of Public Health, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil
av Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
aw Department of Medical Microbiology, Excellence Center for Medical Mycology, Radboudumc-CWZ Center of Expertise for Mycology, Radboud University Medical Center, Nijmegen, Netherlands
ax Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada
ay Department of Clinical Medicine, Federal University of Health Sciences of Porto Alegre Porto Alegre, Brazil
az Molecular Biology Laboratory, Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil
* Correspondence to: Prof George R Thompson III, Department of Internal Medicine, Division of Infectious Diseases, UC Davis Medical Center, Sacramento, CA 95817, USA Department of Internal Medicine Division of Infectious Diseases UC Davis Medical Center Sacramento CA 95817 USA
Summary |
The global burden of the endemic mycoses (blastomycosis, coccidioidomycosis, emergomycosis, histoplasmosis, paracoccidioidomycosis, sporotrichosis, and talaromycosis) continues to rise yearly and these infectious diseases remain a leading cause of patient morbidity and mortality worldwide. Management of the associated pathogens requires a thorough understanding of the epidemiology, risk factors, diagnostic methods and performance characteristics in different patient populations, and treatment options unique to each infection. Guidance on the management of these infections has the potential to improve prognosis. The recommendations outlined in this Review are part of the “One World, One Guideline” initiative of the European Confederation of Medical Mycology. Experts from 23 countries contributed to the development of these guidelines. The aim of this Review is to provide an up-to-date consensus and practical guidance in clinical decision making, by engaging physicians and scientists involved in various aspects of clinical management.
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Elsevier Ltd. Tous droits réservés.
Vol 21 - N° 12
P. e364-e374 - décembre 2021 Retour au numéro
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