Healthcare-associated COVID-19 in England: A national data linkage study - 23/11/21
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Highlights |
• | This is the first national report of healthcare-associated COVID-19 in England. |
• | Our study covered the first wave of the pandemic, from march to august 2020. |
• | 15% of SARS-CoV-2 infections in patients were hospital-onset healthcare-associated. |
• | These represent less than 1% of the estimated 3 million COVID-19 cases in this period. |
Summary |
Objectives |
Nosocomial transmission was an important aspect of SARS-CoV-1 and MERS-CoV outbreaks. Healthcare-associated SARS-CoV-2 infection has been reported in single and multi-site hospital-based studies in England, but not nationally.
Methods |
Admission records for all hospitals in England were linked to SARS-CoV-2 national test data for the period 01/03/2020 to 31/08/2020. Case definitions were: community-onset community-acquired, first positive test <14 days pre-admission, up to day 2 of admission; hospital-onset indeterminate healthcare-associated, first positive on day 3–7; hospital-onset probable healthcare-associated, first positive on day 8–14; hospital-onset definite healthcare-associated, first positive from day 15 of admission until discharge; community-onset possible healthcare-associated, first positive test ≤14 days post-discharge.
Results |
One-third (34.4%, 100,859/293,204) of all laboratory-confirmed COVID-19 cases were linked to a hospital record. Hospital-onset probable and definite cases represented 5.3% (15,564/293,204) of all laboratory-confirmed cases and 15.4% (15,564/100,859) of laboratory-confirmed cases among hospital patients. Community-onset community-acquired and community-onset possible healthcare-associated cases represented 86.5% (253,582/293,204) and 5.1% (14,913/293,204) of all laboratory-confirmed cases, respectively.
Conclusions |
Up to 1 in 6 SARS-CoV-2 infections among hospitalised patients with COVID-19 in England during the first 6 months of the pandemic could be attributed to nosocomial transmission, but these represent less than 1% of the estimated 3 million COVID-19 cases in this period.
Le texte complet de cet article est disponible en PDF.Keywords : Sars-CoV-2, COVID-19, Healthcare-associated infection, Community-onset infection
Plan
Vol 83 - N° 5
P. 565-572 - novembre 2021 Retour au numéro
Article précédent
- Immunogenicity of mRNA-1273 COVID vaccine after 6 months surveillance in health care workers; a third dose is necessary
- Marie Tré-Hardy, Roberto Cupaiolo, Alain Wilmet, Thomas Antoine-Moussiaux, Andrea Della Vecchia, Alexandra Horeanga, Emmanuelle Papleux, Marc Vekemans, Ingrid Beukinga, Laurent Blairon
- Emergence of SARS-CoV-2 Alpha (B.1.1.7) variant, infection rates, antibody seroconversion and seroprevalence rates in secondary school students and staff: Active prospective surveillance, December 2020 to March 2021, England
- Shamez N. Ladhani, Georgina Ireland, Frances Baawuah, Joanne Beckmann, Ifeanyichukwu O Okike, Shazaad Ahmad, Joanna Garstang, Andrew J Brent, Bernadette Brent, Felicity Aiano, Zahin Amin-Chowdhury, Meaghan Kall, Ray Borrow, Ezra Linley, Maria Zambon, John Poh, Lenesha Warrener, Angie Lackenby, Joanna Ellis, Gayatri Amirthalingam, Kevin E Brown, Mary E Ramsay
Bienvenue sur EM-consulte, la référence des professionnels de santé.