Anaphylaxis : Data Gaps and Research Needs - 23/11/21

Doi : 10.1016/j.iac.2021.10.002

Timothy E. Dribin, MD ^a,^b,^⁎ , Mariana Castells, MD, PhD ^c
^a Division of Emergency Medicine, Cincinnati Children’s Hospital Medical Center, 3244 Burnet Avenue, Cincinnati, OH 45229, USA
^b Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
^c Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Hale BTM Building Room 5002N, 60 Fenwood Road, Boston, MA 02115, USA

^∗Corresponding author. Cincinnati Children’s Hospital, 3244 Burnet Avenue, Cincinnati, OH 45229.Cincinnati Children’s Hospital3244 Burnet AvenueCincinnatiOH45229

Résumé

There are significant anaphylaxis data and knowledge gaps that result in suboptimal patient care and outcomes. To address these gaps there is need for collaborative, multidisciplinary research networks to strategically design practice changing research specific to the following anaphylaxis themes: Population Science, Basic and Translational Sciences, Acute Management, and Long-Term Management. Top priorities are to refine anaphylaxis diagnostic criteria, identify accurate diagnostic and predictive anaphylaxis biomarkers, standardize postanaphylaxis care (observation periods, hospitalization criteria), and determine immunotherapy best practices. Addressing these gaps will result in improved, optimal care and clinical outcomes for patients with or at risk of anaphylaxis.

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Keywords : Anaphylaxis, Basic science, Biomarkers, Emergency department, Long-term management, Population science, Research, Translational science

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Basic and Translational Sciences

Funding: The project described was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health, under Award Number 2UL1TR001425 - 05A1. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The project described was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health, under Award Number 2KL2TR001426 -05A1. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

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Vol 42 - N° 1

P. 187-200 - février 2022 Retour au numéro

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Anaphylaxis : Data Gaps and Research Needs - 23/11/21

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