Predictive value of 4th post-operative-day CRP in the early detection of complications after laparoscopic bowel resection for endometriosis - 15/10/21
, Pauline Dilé b, Yohan Kerbage b, Guillaume Piessen b, d, Valérie Deken c, Pierre Collinet b, d, Chrystèle Rubod b, dBienvenue sur EM-consulte, la référence des professionnels de santé.
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| Iconographies | 2 |
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| Autres | 0 |
Abstract |
Objective |
Post-operative CRP on postoperative day 4 (POD) is used for the early detection of complications after colorectal surgery for cancer, but there is no evidence yet that justifies the use of this marker for bowel resection in case of endometriosis.
Study design |
We retrospectively included 66 consecutive patients who underwent bowel resection for endometriosis (stage 4) in Lille university hospital, France, from August 1, 2015 until January 31, 2017. The composite endpoint of our study included anastomotic leakages, infectious or thrombo-embolic complications, hematomas, bowel stenosis, rectorrhagia, voiding dysfunction, and rehospitalization for related symptoms.
Results |
CRP on POD 4 presents a satisfying area under the curve of 0.85, for the composite endpoint. A CRP cut off value of 56 mg/L yielded a sensitivity of 0.61 (IC95%: 0.36 to 0.83) and a specificity of 0.98 (IC95%: 0.89 to 1). The negative and positive predictive values were 0.87 and 0.92.
Conclusion |
The negative predictive value of the CRP on POD 4 after bowel resection for endometriosis is a useful early indicator for detecting a complication. Therefore, this biomarker might be safely used as an additional criterion for a safe discharge from hospital after colorectal resection in endometriosis.
Le texte complet de cet article est disponible en PDF.Keywords : Endometriosis, CRP, Bowel resection, Anastomotic leak, Post-operative complication
Plan
| Study conducted in Lille, France. |
Vol 50 - N° 9
Article 102148- novembre 2021 Retour au numéro
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