Recent advances in regenerative medicine strategies for cancer treatment - 03/09/21
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Abstract |
Cancer stands as one of the most leading causes of death worldwide, while one of the most significant challenges in treating it is revealing novel alternatives to predict, diagnose, and eradicate tumor cell growth. Although various methods, such as surgery, chemotherapy, and radiation therapy, are used today to treat cancer, its mortality rate is still high due to the numerous shortcomings of each approach. Regenerative medicine field, including tissue engineering, cell therapy, gene therapy, participate in cancer treatment and development of cancer models to improve the understanding of cancer biology. The final intention is to convey fundamental and laboratory research to effective clinical treatments, from the bench to the bedside. Proper interpretation of research attempts helps to lessen the burden of treatment and illness for patients. The purpose of this review is to investigate the role of regenerative medicine in accelerating and improving cancer treatment. This study examines the capabilities of regenerative medicine in providing novel cancer treatments and the effectiveness of these treatments to clarify this path as much as possible and promote advanced future research in this field.
Le texte complet de cet article est disponible en PDF.Graphical Abstract |
Highlights |
• | Regenerative medicine participates in cancer treatment and developing cancer models to understand cancer biology. |
• | Although regenerative medicine suffers from major challenges, several clinical trials resulted in approved marketed products. |
• | Despite all the successes and failures in utilizing available products, future perspectives were widened. |
• | This review investigates the role of regenerative medicine in accelerating and improving cancer treatment. |
Abbreviations : AAVs, APC, ADA, CAR T Cell, CAFs, CSCs, CRISPR, CNT, DMD, DCs, ESCs, ECM, HA, HSCs, GVT, ICM, iPSCs, LLC, MMP, MSCs, MPLA, MSR, NK cells, NSCs, NPs, PAD, PTT, PDT, P I:C, PAA, PEG, PLG, PCL, PLGA, SCID, SMA, SMN1, scFv, TME, TCRs, 3D, 2D, VEGF
Keywords : Cancer treatment, Regenerative medicine, Tissue engineering, Cell therapy, Gene therapy
Plan
Vol 141
Article 111875- septembre 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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