The bioactivity of benzenesulfonyl hydrazones: A short review - 03/09/21
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Abstract |
The synthesis and biological activity evaluation of benzenesulfonyl hydrazones is quite frequently encountered in scientific literature. This class of compounds is very interesting due to the wide spectrum of potential applications in the field of medicinal chemistry. The benzenesulfonyl hydrazones possess mainly antibacterial, antifungal, anticancer, antidepressant properties, activity against Alzheimer's disease, insecticidal activity and ability to inhibit the activity of enzymes. This review is an attempt to gather the literature findings on the most promising bioactive benzenesulfonyl hydrazones.
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Highlights |
• | Examples of bioactive benzenesulfonyl hydrazones are gathered in this review |
• | Potential application of benzenesulfonyl hydrazones in the field of medicinal chemistry is presented. |
• | The benzenesulfonyl hydrazones possess mainly antibacterial, antifungal, anticancer, antidepressant properties, activity against Alzheimer's disease, insecticidal activity and ability to inhibit the activity of enzymes. |
Abbreviations : A. niger, A2780, A549, AChE, AD, Aspergillus spp., B. cinerea, B. subtilis, BChE, BENC-511, C. albicans, C. glabrata, C. lagenarium, C6, CAIX, Candida spp., CNS, Cryptococcus spp., DAN-G, DMSO, DOX, E. coli, E. electricus, E. faecalis, FST, GI50, H2170, HCT-12, h-ecto 5′-NT, HEK-293, HeLa, HepG2, IC50, K. pneumoniae, K562, KG-1, LCLC-103H, M. separata, M. tuberculosis, MAO-A, MAO-B, MCF-10A, MCF-7, MDA-MB-231, MDR, MIAPaCa-2, MIC, MTT, NMDA, NRK-49F, P. aeruginosa, P. fluorescens, PDE4, S. aureus, S. epidermidis, SISO, SK-N-SH, TST, WHO
Keywords : Benzenesulfonyl hydrazones, Tosylhydrazones, Biological activity, Anticancer activity, Antimicrobial activity, Antidepressant activity, Alzheimer's disease, Insecticidal activity, Enzyme inhibition
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Vol 141
Article 111851- septembre 2021 Retour au numéro
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