Clinical outcomes analysis of infertile women with unicornuate uterus in IVF-ET - 20/08/21
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Abstract |
Purpose |
To explore the pregnancy outcomes, and neonatal status, arising from embryo transfer in unicornual uterine infertility patients.
Methods |
We analyzed 2499 cycles of clinical data from in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) from 1st May 2016 to 1st May 2018 in the Reproductive Center of the Third Affiliated Hospital of Zhengzhou University, including 109 women with unicornuate uterus (the observation group) and 2390 women with normally shaped uterus (the control group).
Results |
There were no significant differences in embryo implantation rate, clinical pregnancy rate or miscarriage rate (41.88 % VS 42.36 %, P = 0.904; 48.62 % VS 55.94 %, P = 0.133; 11.01 % VS 8.99 %, P = 0.474) between the two groups. The live birth rate in the observation group was lower than that in the control group (35.78 % VS 45.82 %, P = 0.040). The fetal birth weight of the observation group was lower than that of the control group among single-born live births (3009.12 ± 430.59 g VS 3413.40 ± 492.25 g, P = 0.017), but the differences were not observed in the sex ratio at birth, premature birth rate, low birth weight infant (LBW) rate and macrosomia rate (P > 0.05). The fetal birth weight of the observation group was lower than that of the control group among twins live births (2480.00 ± 190.32 g VS 2606.02 ± 471.59 g), but the difference between the groups did not reach statistical significance (P > 0.05)．Logistic regression analysis showed that age, number of embryos transplanted and uterine morphology were independent influencing factors of live birth.
Conclusion |
Compared with women with normal uterus, the live birth rate of women with unicornuate uterus is low, and the birth weight of newborns with single birth is reduced.
Le texte complet de cet article est disponible en PDF.Keywords : Unicornuate uterus, Embryo transfer, Live birth rate, Birth weight
Plan
Vol 50 - N° 7
Article 102111- septembre 2021 Retour au numéro
Article précédent
- Comparison of vaginal progesterone gel combined with oral dydrogesterone versus intramuscular progesterone for luteal support in hormone replacement therapy-frozen embryo transfer cycle
- Hong Xu, Xi-qian Zhang, Xiu-lan Zhu, Hui-nan Weng, Li-qing Xu, Li Huang, Feng-hua Liu
- Office hysteroscopy before first in vitro fertilization. A randomized controlled trial
- Haifa Ben Abid, Myriam Fekih, Khadija Fathallah, Salma Chachia, Mohamed Bibi, Hedi Khairi
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