Major pulmonary complications following Hematopoietic stem cell transplantation: What the pulmonologist needs to know - 18/08/21
Abstract |
Hematopoietic stem cell transplantation (HSCT) is used for treatment of a myriad of both malignant and non-malignant disorders. However, despite many advances over the years which have resulted in improved patient mortality, this subset of patients remains at risk for a variety of post-transplant complications. Pulmonary complications of HSCT are categorized into infectious and non-infectious and occur in up to one-third of patients undergoing HSCT. Infectious etiologies include bacterial, viral and fungal infections, each of which can have significant mortality if not identified and treated early in the course of infection. Advances in the diagnosis and management of infectious complications highlight the importance of non-infectious pulmonary complications related to chemoradiation toxicities, immunosuppressive drugs toxicities, and graft-versus-host disease. This report aims to serve as a guide and clinical update of pulmonary complications following HSCT for the general pulmonologist who may be involved in the care of these patients.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Hematopoietic Stem Cell Transplantation is a therapeutic modality for a variety of malignant and non-malignant conditions. |
• | Pulmonary complications are a major cause of morbidity and mortality in this patient population. |
• | There have been significant advances in prophylaxis, diagnosis & management of respiratory infections following transplant. |
• | Noninfectious pulmonary complications following transplant continue to be a therapeutic challenge. |
• | The management of pulmonary complications requires collaboration between pulmonologists and other specialists. |
Keywords : Pulmonary, Complications, Hematopoietic stem cell transplantation
Plan
Vol 185
Article 106493- août 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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