Benefits of pulmonary rehabilitation in COPD patients with mild cognitive impairment – A pilot study - 18/08/21
Abstract |
Background |
Cognitive impairment might interfere with the efficacy of Pulmonary Rehabilitation (PR) in Chronic Obstructive Pulmonary Disease (COPD). We aimed to identify differential responses to PR between cognitively impaired (CI) and cognitively normal (CN) COPD patients by assessing health status and exercise capacity.
Methods |
Sixty patients (FEV1: 47 ± 15%) were classified as CI or CN according to the Montreal Cognitive Assessment (MoCA ≤25points) and completed a 3-week inpatient PR program. Cognitive function (neuropsychological battery), health-status (36-Item Short Form Survey [SF-36]), and exercise capacity (6-min walk test [6MWT], cycle-endurance test [CET]) were assessed before and after PR. Responsiveness to PR was estimated by mean change (delta-value [Δ]) and the d-Effect Size (ES).
Results |
Twenty-five COPD patients (42%) presented evidence of mild CI prior to PR. Both, CI and CN patients significantly improved global cognitive function, health status (the majority of SF-36 components), and exercise capacity (6MWT and cycle endurance) in response to PR. Compared to CN, CI patients did not improve SF-36 subdomains of “role emotional” and “bodily pain”, and demonstrated a lower magnitude of improvement in 6MWT ([Δ]: 25 m; ES: 0.21) compared to CN ([Δ]: 46 m; ES: 0.54).
Conclusions |
PR has favorable effects on global cognitive function, health status, and exercise capacity in both CI and CN COPD patients. There was no concrete evidence to indicate interference of cognitive impairment to PR effectiveness.
Le texte complet de cet article est disponible en PDF.Highlights |
• | PR is an effective treatment in COPD for both CI and CN patients. |
• | A 3-week PR program has favorable effects on health status in both CI and CN COPDs. |
• | A 3-week PR program has favorable effects on exercise capacity in both CI/CN COPDs. |
• | Persisting bodily pain of COPDs with CI may need special consideration in PR. |
Keywords : Cognitive function, Health status, Exercise capacity, Chronic pain, Chronic obstructive pulmonary disease
Plan
Vol 185
Article 106478- août 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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