Retrospective serosurveillance for anti-SARS-CoV-2 immunoglobulin during a time of low prevalence: A cautionary tale - 19/06/21
Doi : 10.1016/j.jinf.2021.03.007
Paul William Bird a, ⁎ 
, Christopher Holmes a, b, Oliver Fletcher a, Vinay Badhwar c, Oliver Toovey d, Julian Wei-Tze Tang b
, Christopher Holmes a, b, Oliver Fletcher a, Vinay Badhwar c, Oliver Toovey d, Julian Wei-Tze Tang b a Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom
b Respiratory Sciences, University of Leicester, LE1 9HN, United Kingdom
c Intensive Care Unit, University Hospitals of Leicester NHS Trust, Leicester, Royal Infirmary, LE1 5WW Leicester, United Kingdom
d Clinical Virology, University Hospitals 24 of Leicester NHS Trust, Leicester, Royal Infirmary, LE1 5WW Leicester, United Kingdom
⁎Corresponding author.
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Summary |
We performed a retrospective screening of 428 serum samples for anti-SARS-CoV-2 immunoglobulin during a period of low prevalence. Employing two different serological tests yielded discrepant results for 10 samples; highlighting an increased risk of potential false positive results and the need for further confirmatory testing before publication of data.
Le texte complet de cet article est disponible en PDF.Keywords : Serological testing, SARS-CoV-2, Low prevalence
Plan
Crown Copyright © 2021
Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 83 - N° 1
P. 119-145 - juillet 2021 Retour au numéro
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