Subepithelial autoimmune blistering dermatoses: Clinical features and diagnosis - 07/06/21

Doi : 10.1016/j.jaad.2020.11.076

Carmen M. Montagnon, MD ^a, Stanislav N. Tolkachjov, MD ^b,^⁎ , Dedee F. Murrell, MA, BMBCh, MD ^c, Michael J. Camilleri, MD ^a,^d, Julia S. Lehman, MD ^a,^d
^a Department of Dermatology, Mayo Clinic, Rochester, Minnesota
^b Epiphany Dermatology, Dallas, Texas
^c Department of Dermatology, St. George Hospital, University of New South Wales, Sydney, Australia
^d Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

^∗Correspondence and reprint requests to: Stanislav N. Tolkachjov, MD, Epiphany Dermatology, 1640 FM 544. Ste 100, The Colony, TX 75056.Epiphany Dermatology1640 FM 544. Ste 100The ColonyTX75056

Abstract

Subepithelial autoimmune blistering dermatoses are a group of rare skin disorders that are characterized by the disruption of the dermal-epidermal junction through the action of autoantibodies. The third article in this continuing medical education series explores the background, epidemiology, clinical features, and diagnostic criteria of each of the major subepithelial autoimmune blistering dermatoses, including bullous pemphigoid, pemphigoid gestationis, lichen planus pemphigoides, mucous membrane pemphigoid, linear IgA bullous dermatosis, and dermatitis herpetiformis.

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Key words : bullous pemphigoid, bullous eruption of systemic lupus erythematosus, dermatitis herpetiformis, drug-induced bullous pemphigoid, epidermolysis bullosa acquisita, herpes gestationis, linear IgA bullous dermatosis, lichen planus pemphigoides, mucous membrane pemphigoid

Abbreviations used : DH, DIF, ELISA, BMZ, BP, EBA, IIF, LABD, LP, LPP, MMP, nBP, PG, SLE