Discordant cardiac chamber remodeling - 03/06/21
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Résumé |
Introduction |
Background: Left atrial (LA) et left ventricle (LV) enlargement are compensatory mechanisms in chronic mitral regurgitation (MR) due to mitral valve prolapse (MVP).
Purpose |
To evaluate echocardiographic profile and prognostic value of LA and LV remodeling in PVM patients with MR.
Method |
Four hundred and fourteen patients with MVP who had standard echocardiography (GE vivid 7 and 9) at Nancy university hospital were included. Chamber assessment was performed according to guidelines. Clinical characteristics and echocardiographic data were compared between four groups: patients with non-dilated chambers (ND group1, n=135), patients with isolated dilated LA (LA volume>40ml/m2, LA group2, n=100), patients with dilated LV (LVESD (>35ml/M2, LV group3, n=48), and patient with both dilated LA and LV (LA-LV group4, n=131).
Results |
Group1 had more frequently hypertension, (P<0.0001). Group3 had more frequent premature ventricular contractions (PVCs) and more dyspnea (all P<0.0001). Group4 is associated with male sex and severe MR, (all P<0.0001) (Table 1).
Conclusion |
Our study confirms that baseline characteristics of the patients (gender, hypertension) and specific features of MVP (symptoms, arrhythmias and severity of MR) may at least partly explain the different phenotypes of MVP regarding LA and LV remodeling.
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Vol 13 - N° 3
P. 243 - juin 2021 Retour au numéro
Article précédent
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- F. Levy, L. Iacuzio, F. Civaia, F. Wautot, A. Eker
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