Platelet-rich Plasma and Cell Therapy : The New Horizon in Hair Loss Treatment - 28/05/21

Doi : 10.1016/j.det.2021.04.001

Aditya K. Gupta, MD, PhD ^a,^b,^⁎ , Helen J. Renaud, PhD ^b, Jeffrey A. Rapaport, MD ^c
^a Division of Dermatology, Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada
^b Mediprobe Research Inc., 645 Windermere Road, London, Ontario N5X 2P1, Canada
^c Cosmetic Skin and Surgery Center, 333 Sylvan Avenue, Suite 207, Englewood Cliffs, NJ 07632, USA

^∗Corresponding author. Mediprobe Research Inc., 645 Windermere Road, London, Ontario N5X 2P1, Canada.Mediprobe Research Inc.645 Windermere RoadLondonOntarioN5X 2P1Canada

Résumé

Current medicinal therapies for treating hair loss have shortcomes due to variability and ineffectiveness, noncompliance, and adverse effects. The prevalence of hair loss and its associated negative psychological impact have driven research into regenerative medicine approaches, such as platelet-rich plasma (PRP) and cell-based therapies, in an attempt to find alternative, safe, effective, and reproducible treatments. Current research shows promising results from these therapies; however, more robust trials are needed to confirm the reported efficacies of PRP and cell-based therapies. Moreover, standardization of treatment preparation as well as dose and regimen are needed.

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Keywords : Platelet-rich plasma, Cell therapy, Exosomes, Androgenetic alopecia, Alopecia areata