Comprehensive Assessment of Right Ventricular Function by Three-Dimensional Speckle-Tracking Echocardiography: Comparisons with Cardiac Magnetic Resonance Imaging - 03/05/21
Abstract |
Background |
Three-dimensional speckle-tracking echocardiography (3D-STE) has been increasingly used to quantify right ventricular (RV) function. However, direct comparisons of 3D-STE with cardiac magnetic resonance (CMR) imaging for evaluation of RV function are limited. This study aimed to test the feasibility and accuracy of 3D-STE for the quantification of RV volumes, ejection fraction (EF), and longitudinal strain in comparison with CMR imaging and to determine whether 3D-STE for RV strain is superior to two-dimensional (2D) STE in comparison with CMR imaging.
Methods |
A total of 195 consecutive patients referred for both CMR imaging and echocardiography were studied. Right ventricular end-diastolic volume (RVEDV), RV end-systolic volume (RVESV), RVEF, and 3D RV longitudinal strain (3D-RVLS) of the free wall by 3D-STE and 2D-RVLS of the free wall by 2D-STE, were compared with CMR measurements. Pearson correlation and Bland-Altman analyses were used to assess the intertechnique agreement.
Results |
Right ventricular 3D-STE was feasible in 174 patients (89%). Right ventricular volumes and EF determined by 3D-STE strongly correlated with CMR values (RVEDV, r = 0.94; RVESV, r = 0.96; RVEF, r = 0.91; all P < .001). Three-dimensional STE slightly underestimated the RV volumes and longitudinal strain and overestimated the RVEF. The 3D-RVLS values correlated better than 2D-RVLS values with CMR values (0.85 vs 0.64, P < .001) with smaller bias and narrower limits of agreement (bias: 2.0 and 2.6; limits of agreement: 8.5 and 12.5, respectively). The bias and limits of agreement for 3D-STE-obtained RVLS were increased in patients with RV dilation, RVEF < 45%, or lower frame rate compared with those with normal RV size, RVEF ≥ 45%, or higher frame rate, respectively. Right ventricular 3D-STE measurements were highly reproducible.
Conclusions |
The 3D-STE measurements of RV volumes, EF, and longitudinal strain are highly feasible and reproducible, and data measured by 3D-STE correlate strongly with those determined using CMR imaging. Thus, 3D-STE may be a valid alternative to CMR imaging for the quantification of RV function in everyday clinical practice.
Le texte complet de cet article est disponible en PDF.Highlights |
• | RV volumes, EF, and longitudinal strain by 3D-STE are highly feasible and reproducible. |
• | RV volumes, EF, and longitudinal strain by 3D-STE strongly correlate with CMR values. |
• | 3D-STE is superior to 2D-STE for quantifying RV strain using CMR as a reference. |
• | 3D-STE may be a valid alternative to CMR imaging for the RV function assessment. |
Keywords : Speckle-tracking echocardiography, Three-dimensional, Right ventricular function, Longitudinal strain, Magnetic resonance imaging
Abbreviations : 2D, 3D, CMR, ECG, EF, FR, ICC, LOA, LV, RV, RVEDV, RVEDVi, RVEF, RVESV, RVLS, SD, STE
Plan
| Y.L., L.Z., Y.G., X.W., and Q.X contributed equally to this manuscript. |
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| Conflicts of Interest: None. |
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| This work was supported by the National Natural Science Foundation of China (grant nos. 81401432, 81727805, 81922033, 82001852), Natural Science Foundation of Hubei (grant no. 2019CFB474), and Free Innovation Foundation of Union Hospital (grant no. 02.03.2019-133). |
Vol 34 - N° 5
P. 472-482 - mai 2021 Retour au numéro
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